Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL2975678 | 0.97 | — | — | |
| Tetrahydrofuran SCHEMBL28820736 | 0.93 | — | — | |
| Tetrahydrofuran SCHEMBL3618483 | 0.90 | ALDH1A1 (0.57) | ALDH1A1TSHRTTR | |
| Tetrahydrofuran SCHEMBL28088571 | 0.85 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| Tetrahydrofuran SCHEMBL11521890 | 0.82 | — | — | |
| Tetrahydrofuran SCHEMBL193538 | 0.82 | — | — | |
| Dioxane SCHEMBL3093215 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRTTR | |
| Chloromethane SCHEMBL27584162 | 0.82 | — | — | |
| Tetrahydrofuran SCHEMBL2812148 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TSHRTTR | |
| Isopropyl Alcohol SCHEMBL9004332 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TSHRTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399455-B2 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-20100234356-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
| US-4033981-A | ANTIHISTOMINIC, ANTIINFLAMMATORY, SEDATIVES, DIURETICS | WARNER-LAMBERT COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234356-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | ACKR3, CCR5, CXCR2 | ALDH1A1 1889/4885TSHR 696/4885TTR 4778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.