⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinamide SCHEMBL9869222 | 0.78 | LMNA (0.61) | — | |
| SCHEMBL3288573 | 0.78 | ALDH1A1 (0.40) | — | |
| SCHEMBL15776172 | 0.78 | — | — | |
| Succinamide SCHEMBL29135732 | 0.77 | FFAR3 (0.62) | — | |
| Succinamide SCHEMBL5917386 | 0.76 | CYP1A2 (0.42) | — | |
| Succinamide SCHEMBL27460624 | 0.76 | FFAR3 (0.50) | — | |
| Succinamide SCHEMBL5391162 | 0.76 | ALDH1A1 (0.43) | — | |
| Succinamide SCHEMBL5382675 | 0.76 | ALDH1A1 (0.43) | — | |
| Succinamide SCHEMBL28644546 | 0.76 | FFAR3 (0.50) | — | |
| Succinamide SCHEMBL36057 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011272-A | Pyrazines derivatives | 霍夫曼-拉罗奇有限公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-106349156-A | Pyridine-2-amides capable of being used as CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-103608332-B | Pyridine-2-amides useful as CB2 agonists | 霍夫曼-拉罗奇有限公司 | 2016-09-28 | — | — | CN | disclosed |