Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7814389 | 0.84 | ALDH1A1 (0.44) | CA2CA1ALDH1A1L3MBTL1THRB | |
| Trifluoroacetic Acid SCHEMBL30657022 | 0.84 | — | — | |
| Trifluoroacetic Acid SCHEMBL4598430 | 0.84 | — | — | |
| Trifluoroacetic Acid SCHEMBL2484766 | 0.84 | ALDH1A1 (0.44) | CA2CA1ALDH1A1L3MBTL1THRB | |
| Trifluoroacetic Acid SCHEMBL474 | 0.84 | — | — | |
| Trifluoroacetic Acid SCHEMBL23043250 | 0.81 | ALDH1A1 (0.42) | CA2CA1ALDH1A1L3MBTL1THRB | |
| Trifluoroacetic Acid SCHEMBL21802705 | 0.81 | ALDH1A1 (0.42) | CA2CA1ALDH1A1L3MBTL1THRB | |
| Trifluoroacetic Acid SCHEMBL20541014 | 0.81 | — | — | |
| Trifluoroacetic Acid SCHEMBL22712611 | 0.81 | — | — | |
| Trifluoroacetic Acid SCHEMBL20571142 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369783-A | A kind of polypeptide RDP1 and its method of purification and application | 昆明医科大学 | 2019-02-22 | — | — | CN | claimed |
| CN-107236539-A | A kind of aggregation-induced emission antibacterial polypeptide probe and preparation and application | 华南理工大学 | 2017-10-10 | — | — | CN | claimed |
| CN-110325534-A | Substituted imidazoquinolines as NLRP3 modulators | 先天肿瘤免疫公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-110267964-A | Alkylamide substituted heteroaryl phosphine oxide compounds as IL-12, IL-23 and/or IFN α response modulators | 百时美施贵宝公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110243952-A | A method of using each component content of AGEs in HPLC-MS/MS standard measure measurement milk powder | 南京市产品质量监督检验院 | 2019-09-17 | — | — | CN | disclosed |
| CN-110016020-A | Compound or pharmaceutically acceptable salt thereof, application and pharmaceutical composition thereof | 铁木医药有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-109963870-A | ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | 艾伯维公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-109563168-A | ANTI-EGFR ANTIBODY DRUG CONJUGATES | 艾伯维公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109526219-A | Benzsulfamide and its purposes as therapeutic agent | 泽农医药公司 | 2019-03-26 | — | — | CN | disclosed |
| CN-106061971-B | Pyrrolidinyl sulfone derivatives and their use as ROR gamma modulators | 百时美施贵宝公司 | 2019-03-12 | — | — | CN | disclosed |
| CN-109384778-A | Use of a compound or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of a disease, health condition or disorder | 铁木医药有限公司 | 2019-02-26 | — | — | CN | disclosed |
| CN-106715418-A | Therapeutic compounds and methods of use thereof | 基因泰克公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-104136431-B | Pyridone and pyrimidone derivatives as plasma thromboplastin antecedent a inhibitor | 小野药品工业株式会社 | 2017-03-15 | — | — | CN | disclosed |
| CN-106478771-A | A kind of synthetic method of amino acid neural tetrapeptide | 李世军 | 2017-03-08 | — | — | CN | disclosed |
| CN-106279354-A | A kind of synthetic method of amino acid neural dipeptides | 温州医科大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-103842472-B | Biocompatible nanoparticles with aggregation-induced emission properties for use as fluorescent bioprobes and methods of use thereof in vitro/in vivo imaging | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-11-30 | — | — | CN | disclosed |
| CN-106061971-A | Pyrrolidinyl sulfone derivatives and their use as ROR gamma modulators | 百时美施贵宝公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-106039325-A | Fluorescent biological probe and imaging method | 香港科技大学 | 2016-10-26 | — | — | CN | disclosed |
| CN-102863432-B | CFTR conditioning agent | 沃泰克斯药物股份有限公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-103304660-B | A kind of synthetic method of Arg34Lys26-(N-EPSILON-(N-ALPHA-Palmitoyl-L-GAMMA-glutamyl))-GLP-1[7-37] | 上海昂博生物技术有限公司 | 2016-08-10 | — | — | CN | disclosed |