Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL769278 | 0.77 | GAA (0.48) | MAPTKDM4ENLRP3CASP1HSD17B10 | |
| SCHEMBL2167246 | 0.76 | NLRP3 (0.51) | KDM4ENLRP3CASP1HSD17B10L3MBTL1 | |
| SCHEMBL6829396 | 0.73 | MAPT (0.50) | MAPTKDM4EPOLBTSHRCASP1 | |
| SCHEMBL4859694 | 0.73 | MAPT (0.35) | MAPTKDM4EPOLBTSHRCASP1 | |
| Water SCHEMBL28215001 | 0.72 | KDM4E (0.56) | MAPTKDM4EPOLBTSHRCASP1 | |
| SCHEMBL12214120 | 0.72 | KDM4E (0.42) | MAPTKDM4EPOLBTSHRL3MBTL1 | |
| SCHEMBL6471568 | 0.70 | CTBP2 (0.46) | MAPTKDM4ENPC1CASP7MEN1 | |
| SCHEMBL6829455 | 0.70 | HSP90AB1 (0.41) | MAPTKDM4ETSHRCASP1HSD17B10 | |
| SCHEMBL10786053 | 0.70 | NLRP3 (0.34) | MAPTKDM4ENLRP3POLBL3MBTL1 | |
| SCHEMBL27945458 | 0.70 | CYP1A2 (0.33) | KDM4ENLRP3HSD17B10ALDH1A1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103402979-B | Chemical compound | 先正达参股股份有限公司 | 2016-08-24 | — | — | CN | disclosed |