Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | CASP1 | P29466 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL769278 | 0.83 | GAA (0.48) | MAPTHSD17B10NPC1CASP1NPSR1 | |
| SCHEMBL509922 | 0.82 | MAPT (0.46) | MAPTHSD17B10NPC1CASP1TSHR | |
| SCHEMBL6829455 | 0.79 | HSP90AB1 (0.41) | MAPTHSD17B10NPC1CASP1TSHR | |
| SCHEMBL6834789 | 0.76 | KDM4E (0.43) | MAPTHSD17B10NPC1CASP1NPSR1 | |
| SCHEMBL6921814 | 0.76 | ALDH1A1 (0.45) | MAPTHSD17B10CASP1NPSR1KMT2A | |
| SCHEMBL6834766 | 0.76 | TSHR (0.45) | MAPTHSD17B10CASP1TSHRNPSR1 | |
| SCHEMBL1224633 | 0.76 | KDM4E (0.43) | MAPTHSD17B10NPC1CASP1TSHR | |
| SCHEMBL14661541 | 0.74 | P2RX7 (0.44) | MAPTHSD17B10NPC1TSHRNPSR1 | |
| SCHEMBL28089217 | 0.73 | MAPT (0.34) | MAPTHSD17B10NPC1CASP1TSHR | |
| SCHEMBL6832152 | 0.73 | GPR35 (0.38) | MAPTHSD17B10NPC1CASP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6746990-B2 | INSECTICIDES, ACARICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-08 | — | — | US | disclosed |
| US-20030045432-A1 | Phenyl-substituted cyclic ketoenols | FISCHER REINER (DE) | 2003-03-06 | — | — | US | disclosed |
| US-6358887-B1 | PREEMERGENCE, POSTEMERGENCE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045432-A1 | Phenyl-substituted cyclic ketoenols | CYP19A1, DDT, CYP8B1 | MAPT 4613/4885HSD17B10 246/4885NPC1 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.