SCHEMBL28089288

SCHEMBL28089288

COc1c[c]cc(OC)c1.[CaH2]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
CYP1A1 P04798 6/20 0.42
CYP1B1 Q16678 6/20 0.42
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
CYP1A2 P05177 4/20 0.37
CYP3A4 P08684 3/20 0.37
CYP2A6 P11509 3/20 0.37
CYP2E1 P05181 2/20 0.37
CYP2C8 P10632 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP4B1 P13584 2/20 0.37
CYP2B6 P20813 2/20 0.37
CYP3A5 P20815 2/20 0.37
CYP2A7 P20853 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL63193 0.97 ALDH1A1 (0.59) ALDH1A1CYP1A1CYP1B1CA12CA1
SCHEMBL28007784 0.94 ALDH1A1 (0.56) ALDH1A1CYP1A1CYP1B1CA12CA1
SCHEMBL28321856 0.94 ALDH1A1 (0.56) ALDH1A1CYP1A1CYP1B1CA12CA1
SCHEMBL28108949 0.94 ALDH1A1 (0.56) ALDH1A1CYP1A1CYP1B1CA12CA1
SCHEMBL27957637 0.87 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1B1CA12CA1
SCHEMBL499727 0.83 ESR1 (0.47) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL161853 0.81
SCHEMBL9254 0.81
SCHEMBL16959383 0.81 ALDH1A1 (0.42) ALDH1A1CYP1A1CYP1B1CA12CA1
SCHEMBL7389057 0.81 ALDH1A1 (0.42) ALDH1A1CYP1A1CYP1B1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105829329-A Phosphinyl formamidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins 切弗朗菲利浦化学公司 2016-08-03 CN disclosed