SCHEMBL63193

SCHEMBL63193

COc1c[c]cc(OC)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.59
CYP1A1 P04798 6/20 0.43
CYP1B1 Q16678 6/20 0.43
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CYP1A2 P05177 4/20 0.39
CYP3A4 P08684 3/20 0.39
CYP2A6 P11509 3/20 0.39
CYP2E1 P05181 2/20 0.39
CYP2C8 P10632 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP4B1 P13584 2/20 0.39
CYP2B6 P20813 2/20 0.39
CYP3A5 P20815 2/20 0.39
CYP2A7 P20853 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28089288 0.97 ALDH1A1 (0.56) ALDH1A1CYP1A1CYP1B1CA12CA1
SCHEMBL28321856 0.97 ALDH1A1 (0.56) ALDH1A1CYP1A1CYP1B1CA12CA1
SCHEMBL28007784 0.97 ALDH1A1 (0.56) ALDH1A1CYP1A1CYP1B1CA12CA1
SCHEMBL28108949 0.97 ALDH1A1 (0.56) ALDH1A1CYP1A1CYP1B1CA12CA1
SCHEMBL27957637 0.89 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1B1CA12CA1
SCHEMBL499727 0.85 ESR1 (0.47) ALDH1A1CYP1A1CYP1B1CYP1A2CYP3A4
SCHEMBL9254 0.84
SCHEMBL161853 0.84
SCHEMBL16959383 0.83 ALDH1A1 (0.42) ALDH1A1CYP1A1CYP1B1CA12CA1
SCHEMBL7389057 0.83 ALDH1A1 (0.42) ALDH1A1CYP1A1CYP1B1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6527 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344379-A Diversity-oriented synthesis and activity research of alpha-carboline and beta-carboline-1-ketone derivatives 重庆医科大学 2024-07-16 CN claimed
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
CN-118307532-A N2 substituted triazole-oxazoline chiral compound and preparation method and application thereof 吉林大学 2024-07-09 CN claimed
CN-118206551-A Quinoline compounds, their preparation and their use as antimalarial agents 美国卫生和人力服务部 2024-06-18 CN claimed
CN-113874353-B Microbiocidal derivatives 先正达农作物保护股份公司 2024-06-14 CN claimed
US-20240174603-A1 MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME RAPPTA THERAPEUTICS OY (FI) 2024-05-30 US claimed
CN-116969996-B Ethylene selective trimerization catalytic ligand, preparation method, catalytic system and application thereof 卫星化学股份有限公司 2024-05-03 CN claimed
CN-115974919-B 2- (Triphenylphosphine) benzenesulfonate derivative and preparation method thereof 石河子大学 2024-04-16 CN claimed
CN-117777121-A Compounds and uses thereof 詹森药业有限公司 2024-03-29 CN claimed
CN-110770214-B Heterocyclic P2X7 antagonists 布雷耶疗法有限公司 2024-03-29 CN claimed
US-4440845-A CHARGE TRANSFER COMPOUND RICOH CO., LTD. (JP) 1984-04-03 US claimed
EP-0096993-A2 Phosphoramidothionate, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-12-28 EP claimed
US-4351843-A LOWERING BLOOD GLUCOSE PFIZER INC. (US) 1982-09-28 US claimed
EP-0048615-A1 Improvements in or relating to 3-aryl-5-isothiazole derivatives ELI LILLY AND COMPANY (US) 1982-03-31 EP claimed
US-4179466-A Phthalic dianilides MONSANTO COMPANY (US) 1979-12-18 US claimed
US-4178442-A ANTIANGOROUS ACTIVITY DELALANDE S. A. (FR) 1979-12-11 US claimed
US-4146386-A Phthalic dianilides and their use as plant growth regulators MONSANTO COMPANY (US) 1979-03-27 US claimed
US-4118561-A ANTIBACTERIAL, SYNERGISTIC, ANTI-CANCER ACTIVITY, ANTI-FOLIC ACID ACTIVITY AMERICAN HOME PRODUCTS CORPORATION (US) 1978-10-03 US claimed
US-4001426-A HAVING CORONARY VASODILATOR ACTIVITY SMITHKLINE CORPORATION (US) 1977-01-04 US claimed
US-3953432-A OXAZOLINE DERIVATIVES COMMERCIAL SOLVENTS CORPORATION (US) 1976-04-27 US claimed