Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30520870 | 0.89 | TAAR1 (0.61) | TAAR1AOC3IDO1SIGMAR1KMT2A | |
| SCHEMBL267933 | 0.89 | TAAR1 (0.61) | TAAR1AOC3IDO1SIGMAR1KMT2A | |
| SCHEMBL19398947 | 0.86 | TAAR1 (0.56) | TAAR1AOC3IDO1SIGMAR1MPO | |
| SCHEMBL7831226 | 0.81 | TAAR1 (0.69) | TAAR1AOC3IDO1SIGMAR1MPO | |
| SCHEMBL9627286 | 0.80 | TAAR1 (0.50) | TAAR1AOC3SIGMAR1MPOCA12 | |
| SCHEMBL27755262 | 0.80 | TAAR1 (0.50) | TAAR1AOC3MPOCA12CA1 | |
| SCHEMBL11742522 | 0.79 | TAAR1 (0.53) | TAAR1AOC3SIGMAR1MPO | |
| SCHEMBL5520311 | 0.79 | TAAR1 (0.49) | TAAR1AOC3IDO1SIGMAR1MPO | |
| SCHEMBL14655700 | 0.78 | KMT2A (0.64) | TAAR1HTR2AIDO1KMT2A | |
| SCHEMBL31689750 | 0.78 | TAAR1 (0.78) | TAAR1AOC3IDO1SIGMAR1MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109745313-A | The D3 dopamine-receptor stimulant for treating dyskinesia in Parkinson's disease | 德雷克塞尔大学 | 2019-05-14 | — | — | CN | claimed |
| CN-105848655-B | For attention and cognitive disorder and for dementia associated with neurodegeneration obstacle new treatment | 德雷克塞尔大学 | 2019-11-08 | — | — | CN | disclosed |
| CN-109745313-A | The D3 dopamine-receptor stimulant for treating dyskinesia in Parkinson's disease | 德雷克塞尔大学 | 2019-05-14 | — | — | CN | disclosed |
| CN-103347517-B | Treatment of dyskinesia in Parkinson's disease D3Dopamine receptor agonists | 德雷克塞尔大学 | 2018-10-02 | — | — | CN | disclosed |
| CN-105848655-A | Novel treatments for attention and cognitive disorders, and for dementia associated with a neurodegenerative disorder | 德雷克塞尔大学 | 2016-08-10 | — | — | CN | disclosed |