Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487002 | 0.84 | TAAR1 (0.45) | TAAR1SIGMAR1 | |
| SCHEMBL31332097 | 0.84 | ALOX5 (0.38) | MPOBCHE | |
| SCHEMBL19398947 | 0.83 | TAAR1 (0.56) | TAAR1MPOMTNR1AMTNR1BSIGMAR1 | |
| SCHEMBL28089294 | 0.80 | TAAR1 (0.58) | TAAR1MPOSIGMAR1AOC3CA12 | |
| Methoxyphenamine SCHEMBL29390678 | 0.80 | TAAR1 (0.50) | TAAR1SIGMAR1 | |
| Methoxyphenamine SCHEMBL218289 | 0.80 | TAAR1 (0.50) | TAAR1SIGMAR1 | |
| Methoxyphenamine SCHEMBL14655868 | 0.80 | TAAR1 (0.50) | TAAR1SIGMAR1 | |
| Methoxyphenamine SCHEMBL2751759 | 0.80 | TAAR1 (0.50) | TAAR1SIGMAR1 | |
| SCHEMBL7831226 | 0.78 | TAAR1 (0.69) | TAAR1MPOMTNR1AMTNR1BSIGMAR1 | |
| Methoxyphenamine SCHEMBL208636 | 0.78 | ALDH1A1 (0.51) | TAAR1SIGMAR1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |