Quinoline

Quinoline

SCHEMBL28089463

CCCCCCn1ccnc1C.c1ccc2ncccc2c1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
KMT2A Q03164 2/20 0.59
POLB P06746 1/20 0.59
TLR8 Q9NR97 5/20 0.46
P2RX7 Q99572 1/20 0.44
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
SLC9A1 P19634 2/20 0.39
TSHR P16473 1/20 0.39
KDM4E B2RXH2 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 1/20 0.38
EEF2K O00418 1/20 0.38
PLK4 O00444 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL27680746 0.95 ALDH1A1 (0.67) ALDH1A1KMT2APOLBTLR8P2RX7
Quinoline SCHEMBL28193443 0.85 ALDH1A1 (0.49) ALDH1A1KMT2APOLBP2RX7CA12
Quinoline SCHEMBL27759111 0.83 ALDH1A1 (0.53) ALDH1A1KMT2APOLBP2RX7L3MBTL1
SCHEMBL5287541 0.83 ALDH1A1 (0.85) ALDH1A1KMT2APOLBTLR8P2RX7
SCHEMBL25270261 0.83 ALDH1A1 (0.85) ALDH1A1KMT2APOLBTLR8P2RX7
SCHEMBL25267924 0.83 ALDH1A1 (0.85) ALDH1A1KMT2APOLBTLR8P2RX7
SCHEMBL25240227 0.83 ALDH1A1 (0.85) ALDH1A1KMT2APOLBTLR8P2RX7
SCHEMBL2328687 0.83 ALDH1A1 (0.85) ALDH1A1KMT2APOLBTLR8P2RX7
SCHEMBL363481 0.83 ALDH1A1 (0.85) ALDH1A1KMT2APOLBTLR8P2RX7
SCHEMBL4070067 0.83 ALDH1A1 (0.85) ALDH1A1KMT2APOLBTLR8P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105830243-A DYE-SENSITIZED SOLAR CELL 株式会社理光 2016-08-03 CN disclosed