Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.85 |
| ▸ | POLB | P06746 | 1/20 | 0.85 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4068798 | 1.00 | ALDH1A1 (0.85) | ALDH1A1KMT2APOLBTLR8CA12 | |
| SCHEMBL5287541 | 1.00 | ALDH1A1 (0.85) | ALDH1A1KMT2APOLBTLR8CA12 | |
| SCHEMBL363481 | 1.00 | ALDH1A1 (0.85) | ALDH1A1KMT2APOLBTLR8CA12 | |
| SCHEMBL25267924 | 1.00 | ALDH1A1 (0.85) | ALDH1A1KMT2APOLBTLR8CA12 | |
| SCHEMBL1137200 | 1.00 | ALDH1A1 (0.85) | ALDH1A1KMT2APOLBTLR8CA12 | |
| SCHEMBL25270261 | 1.00 | ALDH1A1 (0.85) | ALDH1A1KMT2APOLBTLR8CA12 | |
| SCHEMBL25240227 | 1.00 | ALDH1A1 (0.85) | ALDH1A1KMT2APOLBTLR8CA12 | |
| SCHEMBL25267373 | 1.00 | ALDH1A1 (0.85) | ALDH1A1KMT2APOLBTLR8CA12 | |
| SCHEMBL2328687 | 1.00 | ALDH1A1 (0.85) | ALDH1A1KMT2APOLBTLR8CA12 | |
| SCHEMBL634872 | 1.00 | ALDH1A1 (0.85) | ALDH1A1KMT2APOLBTLR8CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117050231-A | Amphiphilic hyperbranched polymer emulsion for oil displacement as well as preparation method and application thereof | 山东聚星石油科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| US-10736904-B2 | Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof | SANOFI (FR) | 2020-08-11 | — | — | US | disclosed |
| US-10220044-B2 | Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof | SANOFI (FR) | 2019-03-05 | — | — | US | disclosed |
| US-20180021723-A1 | GAS TREATING SOLUTIONS CONTAINING IMIDAZOLE-AMINE COMPOUNDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA | 2018-01-25 | — | — | US | disclosed |
| US-20170319594-A1 | NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2017-11-09 | — | — | US | disclosed |
| US-9744176-B2 | Therapeutic uses of novel thienopyrimidine derivatives | SANOFI (FR) | 2017-08-29 | — | — | US | disclosed |
| WO-2009040107-A2 | METHOD FOR THE PRODUCTION OF METAL-CONTAINING NANOPARTICLES | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2009-04-02 | — | — | WO | disclosed |
| WO-2009024312-A2 | METHOD FOR THE PRODUCTION AND STABILIZATION OF FUNCTIONAL METAL NANOPARTICLES IN IONIC LIQUIDS | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2009-02-26 | — | — | WO | disclosed |
| US-5326762-A | Heterocyclic substituted amides | SCHERING CORPORATION (US) | 1994-07-05 | — | — | US | disclosed |
| US-5149709-A | Treatment of atherosclerosis | SCHERING CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0131302-B1 | IMIDAZOLIUM SALTS, INTERMEDIATES THERETO AND THEIR USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-01-29 | — | — | EP | disclosed |
| US-4689341-A | Antiarrhythmic imidazoles | SCHERING A.G. (DE) | 1987-08-25 | — | — | US | disclosed |
| US-4613609-A | Antiarrhythmic imidazoliums | SCHERING A. G. (DE) | 1986-09-23 | — | — | US | disclosed |
| US-4581370-A | Antiarrhythmic imidazoliums | SCHERING A.G. (DE) | 1986-04-08 | — | — | US | disclosed |
| EP-0131302-A2 | Imidazolium salts, intermediates thereto and their use | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10736904-B2 | Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof | DPYD, TYMP, DHFR | ALDH1A1 91/4885KMT2A 3212/4885POLB 706/4885 |
| US-20180021723-A1 | GAS TREATING SOLUTIONS CONTAINING IMIDAZOLE-AMINE COMPOUNDS | NISCH, INMT, GMPS | ALDH1A1 2670/4885KMT2A 770/4885POLB 715/4885 |
| US-20170319594-A1 | NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | DPYD, TYMP, DHFR | ALDH1A1 142/4885KMT2A 3273/4885POLB 708/4885 |
| US-10220044-B2 | Thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof | DPYD, TYMP, DHFR | ALDH1A1 91/4885KMT2A 3212/4885POLB 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.