SCHEMBL28089473

SCHEMBL28089473

COCOCc1ccccc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.53
PNMT P11086 1/20 0.43
MAOB P27338 2/20 0.42
MAOA P21397 1/20 0.42
TAAR1 Q96RJ0 3/20 0.41
MAPT P10636 2/20 0.41
NR4A2 P43354 1/20 0.40
HTR1A P08908 1/20 0.39
ADRA1D P25100 1/20 0.39
ADRA1A P35348 1/20 0.39
ADRA1B P35368 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
AOC3 Q16853 1/20 0.39
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30377 0.83 IDO1 (0.61) IDO1PNMTMAOBMAOATAAR1
SCHEMBL3774965 0.83 IDO1 (0.67) IDO1PNMTMAOBMAOATAAR1
SCHEMBL9419151 0.82 IDO1 (0.52) IDO1PNMTMAOBMAOATAAR1
SCHEMBL28528498 0.82 IDO1 (0.37) IDO1PNMTTAAR1MAPTHTR1A
Phosphine SCHEMBL20719631 0.81 IDO1 (0.59) IDO1PNMTMAOBMAOATAAR1
SCHEMBL6507641 0.79 IDO1 (0.57) IDO1PNMTMAOBMAOATAAR1
SCHEMBL23032125 0.78 IDO1 (0.47) IDO1PNMTMAOBMAOATAAR1
SCHEMBL18892795 0.78 TAAR1 (0.42) MAOBTAAR1MAPTHTR1AADRA1D
SCHEMBL500785 0.76 IDO1 (0.53) IDO1TAAR1MAPTRAB9ANPC1
SCHEMBL15116917 0.76 CYP4F2 (0.39) IDO1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108142434-A For protecting the method for useful plant or plant propagation material 先正达参股股份有限公司 2018-06-12 CN disclosed
CN-106008571-A Boron-containing small molecules 安纳考尔医药公司 2016-10-12 CN disclosed
CN-106008583-A BORON-CONTAINING SMALL MOLECULES 安纳考尔医药公司 2016-10-12 CN disclosed
CN-105949230-A BORON-CONTAINING SMALL MOLECULES 安纳考尔医药公司 2016-09-21 CN disclosed