Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992523 | 0.85 | IDO1 (0.59) | IDO1TAAR1ALDH1A1TSHRMAPT | |
| SCHEMBL1146014 | 0.83 | IDO1 (0.61) | IDO1TAAR1ALDH1A1TSHRMAPT | |
| SCHEMBL3865796 | 0.83 | IDO1 (0.67) | IDO1TAAR1ALDH1A1TSHRMAPT | |
| SCHEMBL18343943 | 0.82 | IDO1 (0.52) | IDO1TAAR1ALDH1A1TSHRMAPT | |
| SCHEMBL500370 | 0.82 | TAAR1 (0.48) | IDO1TAAR1ALDH1A1TSHRMAPT | |
| SCHEMBL12383437 | 0.82 | IDO1 (0.38) | IDO1ALDH1A1TSHRMAPTRAB9A | |
| SCHEMBL9419149 | 0.81 | IDO1 (0.59) | IDO1TAAR1ALDH1A1TSHRMAPT | |
| SCHEMBL18171748 | 0.79 | IDO1 (0.61) | IDO1TAAR1ALDH1A1TSHRMAPT | |
| SCHEMBL18892795 | 0.78 | TAAR1 (0.42) | TAAR1ALDH1A1TSHRMAPTKMT2A | |
| SCHEMBL2400375 | 0.78 | IDO1 (0.55) | IDO1TAAR1ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240358728-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, LLC (US) | 2024-10-31 | — | — | US | disclosed |
| US-20230008130-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2023-01-12 | — | — | US | disclosed |
| EP-3424932-B1 | BORONOPHTHALIDES FOR THERAPEUTIC USE | ANACOR PHARMACEUTICALS INC (US) | 2021-04-07 | — | — | EP | disclosed |
| US-20210070780-A1 | Boron-Containing Small Molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2021-03-11 | — | — | US | disclosed |
| US-20210000847-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2021-01-07 | — | — | US | disclosed |
| US-20200179418-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | US | disclosed |
| US-20200046745-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2020-02-13 | — | — | US | disclosed |
| US-20190330245-A1 | Boron-Containing Small Molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2019-10-31 | — | — | US | disclosed |
| US-20190282594-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2019-09-19 | — | — | US | disclosed |
| US-20190160081-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2019-05-30 | — | — | US | disclosed |
| WO-2007078340-A2 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| US-20070155699-A1 | Boron-containing small molecules | ANACOR PHARMACEUTICALS (US) | 2007-07-05 | — | — | US | disclosed |
| US-20060234981-A1 | Boron-containing small molecules | ANACOR PHARMACEUTICALS (US) | 2006-10-19 | — | — | US | disclosed |
| CN-1829521-A | Hydrolysis resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS INC (US) | 2006-09-06 | — | — | CN | disclosed |
| WO-2006089067-A2 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2006-08-24 | — | — | WO | disclosed |
| EP-1638578-A2 | HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE | Anacor Pharmaceuticals, Inc. (US) | 2006-03-29 | — | — | EP | disclosed |
| US-20050261327-A1 | 2-(Bicyclo)alkylamino-derivatives as mediatores of chronic pain and inflammation | MERCK & CO., INC. | 2005-11-24 | — | — | US | disclosed |
| WO-2005013892-A9 | HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE | ANACOR PHARMACEUTICALS INC (US) | 2005-04-14 | — | — | WO | disclosed |
| US-20050054644-A1 | Hydrolytically-resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS, LLC | 2005-03-10 | — | — | US | disclosed |
| WO-2005013892-A2 | HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE | ANACOR PHARMACEUTICALS, INC. (US) | 2005-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060234981-A1 | Boron-containing small molecules | ETF1, POLR1C, DPM1 | IDO1 352/4885TAAR1 3432/4885ALDH1A1 3692/4885 |
| US-20050261327-A1 | 2-(Bicyclo)alkylamino-derivatives as mediatores of chronic pain and inflammation | BDKRB1, BDKRB2, LTB4R2 | IDO1 864/4885TAAR1 364/4885ALDH1A1 2563/4885 |
| US-20190160081-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | IDO1 1994/4885TAAR1 3568/4885ALDH1A1 3616/4885 |
| US-20190330245-A1 | Boron-Containing Small Molecules | ETF1, POLR1C, DPM1 | IDO1 352/4885TAAR1 3432/4885ALDH1A1 3692/4885 |
| US-20230008130-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | IDO1 1994/4885TAAR1 3568/4885ALDH1A1 3616/4885 |
| US-20200046745-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | IDO1 1994/4885TAAR1 3568/4885ALDH1A1 3616/4885 |
| US-20200179418-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | IDO1 1994/4885TAAR1 3568/4885ALDH1A1 3616/4885 |
| US-20240358728-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | IDO1 1994/4885TAAR1 3568/4885ALDH1A1 3616/4885 |
| US-20070155699-A1 | Boron-containing small molecules | ETF1, POLR1C, DPM1 | IDO1 352/4885TAAR1 3432/4885ALDH1A1 3692/4885 |
| US-20210070780-A1 | Boron-Containing Small Molecules | ETF1, POLR1C, DPM1 | IDO1 352/4885TAAR1 3432/4885ALDH1A1 3692/4885 |
| US-20050054644-A1 | Hydrolytically-resistant boron-containing therapeutics and methods of use | BTD, GAA, GBA3 | IDO1 2697/4885TAAR1 4336/4885ALDH1A1 1632/4885 |
| US-20190282594-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | IDO1 1994/4885TAAR1 3568/4885ALDH1A1 3616/4885 |
| US-20210000847-A1 | BORON CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | NFKBIA, LITAF, LRBA | IDO1 1994/4885TAAR1 3568/4885ALDH1A1 3616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.