Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | HEXA | P06865 | 1/20 | 0.37 |
| ▸ | HEXB | P07686 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 7/20 | 0.35 |
| ▸ | NOS2 | P35228 | 7/20 | 0.35 |
| ▸ | NOS1 | P29475 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089607 | 0.88 | ADORA1 (0.39) | LMNAALDH1A1TSHRADORA2AADORA1 | |
| SCHEMBL15051818 | 0.84 | LMNA (0.48) | LMNAALDH1A1TSHRADORA2AADORA1 | |
| SCHEMBL16652085 | 0.75 | ADORA2A (0.52) | LMNAALDH1A1TSHRADORA2AADORA1 | |
| SCHEMBL28853673 | 0.74 | VRK1 (0.34) | PIK3CDPIK3R1PIK3CGMAPK1 | |
| SCHEMBL28855953 | 0.71 | FYN (0.53) | TSHRPIK3CDPIK3CGKDM4EKDR | |
| SCHEMBL23143466 | 0.68 | LMNA (0.46) | LMNAALDH1A1TSHRADORA2AADORA1 | |
| SCHEMBL2680563 | 0.68 | MAPK1 (0.51) | LMNAALDH1A1TSHRADORA2AADORA1 | |
| SCHEMBL15604777 | 0.68 | TP53 (0.38) | LMNA | |
| SCHEMBL28235663 | 0.68 | CYP2A6 (0.58) | ALDH1A1ADORA2AADORA1NOS3NOS2 | |
| SCHEMBL20522450 | 0.66 | KDM4E (0.49) | ALDH1A1TSHRADORA1PIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109021022-A | Luminous diaza benzo imidazole carbene metal complex | UDC 爱尔兰有限责任公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-105431442-B | Luminescent Diazabenzimidazole Carbene Metal Complexes | UDC 爱尔兰有限责任公司 | 2018-08-07 | — | — | CN | disclosed |
| CN-105764911-A | Luminescent diaza-, monoaza-and benzo-imidazole metal carbene complexes for use in electronic devices such as OLEDs | 巴斯夫欧洲公司 | 2016-07-13 | — | — | CN | disclosed |