Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 4/20 | 0.35 |
| ▸ | NOS2 | P35228 | 4/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089606 | 0.88 | LMNA (0.41) | ADORA1ADORA2AMAPK1KDRLMNA | |
| SCHEMBL15051818 | 0.73 | LMNA (0.48) | ADORA1ADORA2ARXRARXRBLMNA | |
| SCHEMBL17306375 | 0.73 | ALDH1A1 (0.61) | RXRARXRBMEN1KMT2AKDM4E | |
| SCHEMBL3970734 | 0.73 | ALDH1A1 (0.61) | RXRARXRBMEN1KMT2AKDM4E | |
| SCHEMBL7061715 | 0.72 | RAB9A (0.42) | MAPK1KDRLMNAMEN1KMT2A | |
| SCHEMBL2254389 | 0.72 | CCNT1 (0.42) | ADORA1ADORA2AMAPK1LMNAKDM4E | |
| SCHEMBL18448354 | 0.72 | ACHE (0.56) | ADORA1ADORA2AMAPK1LMNAMEN1 | |
| SCHEMBL30610421 | 0.72 | CCNT1 (0.42) | ADORA1ADORA2AMAPK1LMNAKDM4E | |
| SCHEMBL20522349 | 0.72 | KDM4E (0.54) | ADORA1ADORA2AMAPK1KDRKMT2A | |
| SCHEMBL30610423 | 0.72 | KDM4E (0.54) | ADORA1ADORA2AMAPK1KDRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764911-A | Luminescent diaza-, monoaza-and benzo-imidazole metal carbene complexes for use in electronic devices such as OLEDs | 巴斯夫欧洲公司 | 2016-07-13 | — | — | CN | disclosed |