Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | FOS | P01100 | 1/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798136 | 0.87 | NFE2L2 (0.62) | NFE2L2MAOBMAOACYP1A1CYP1A2 | |
| SCHEMBL30749687 | 0.87 | NFE2L2 (0.62) | NFE2L2MAOBMAOACYP1A1CYP1A2 | |
| SCHEMBL10496422 | 0.87 | NFE2L2 (0.62) | NFE2L2MAOBMAOACYP1A1CYP1A2 | |
| SCHEMBL17978233 | 0.85 | CYP1A1 (0.53) | NFE2L2MAOBMAOACYP1A1CYP1A2 | |
| SCHEMBL19810852 | 0.85 | CYP1A1 (0.53) | NFE2L2MAOBMAOACYP1A1CYP1A2 | |
| SCHEMBL5332771 | 0.84 | BACE1 (0.59) | NFE2L2MAOBMAOARELABACE1 | |
| SCHEMBL5343618 | 0.84 | BACE1 (0.59) | NFE2L2MAOBMAOARELABACE1 | |
| SCHEMBL17386262 | 0.84 | ABL1 (0.52) | NFE2L2CYP1A1CYP1A2CYP1B1NR1H3 | |
| SCHEMBL17386261 | 0.84 | ABL1 (0.52) | NFE2L2CYP1A1CYP1A2CYP1B1NR1H3 | |
| SCHEMBL30423635 | 0.84 | BACE1 (0.61) | NFE2L2CYP1A2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104761470-B | The preparation method of (R, S)-2-[[5-(9-fluorenylmethyloxycarbonyl amino) dibenzo [a, d] cycloheptane-2-base] oxygen] acetic acid | 吉尔生化（上海）有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-117510323-B | Preparation method of Ramage Linker intermediate | 成都泰莱康科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117510323-A | Preparation method of Ramage Linker intermediate | 成都泰莱康科技有限公司 | 2024-02-06 | — | — | CN | disclosed |