Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | FOS | P01100 | 1/20 | 0.55 |
| ▸ | JUN | P05412 | 1/20 | 0.55 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30749687 | 1.00 | NFE2L2 (0.62) | NFE2L2BCHEMAOBMAOACYP1A1 | |
| SCHEMBL10496422 | 1.00 | NFE2L2 (0.62) | NFE2L2BCHEMAOBMAOACYP1A1 | |
| SCHEMBL2400866 | 0.89 | NFE2L2 (0.56) | NFE2L2BCHEMAOBMAOACYP1A1 | |
| SCHEMBL2400863 | 0.89 | NFE2L2 (0.56) | NFE2L2BCHEMAOBMAOACYP1A1 | |
| SCHEMBL28089618 | 0.87 | NFE2L2 (0.61) | NFE2L2BCHEMAOBMAOACYP1A1 | |
| SCHEMBL10496482 | 0.85 | ALDH1A1 (0.63) | NFE2L2MAOBMAOARELAMEN1 | |
| SCHEMBL11687899 | 0.85 | NFE2L2 (0.55) | NFE2L2BCHEMAOBMAOACYP1A1 | |
| SCHEMBL9798901 | 0.85 | ALDH1A1 (0.63) | NFE2L2MAOBMAOARELAMEN1 | |
| SCHEMBL28346344 | 0.85 | NFE2L2 (0.55) | NFE2L2BCHEMAOBMAOACYP1A1 | |
| SCHEMBL11687908 | 0.85 | NFE2L2 (0.55) | NFE2L2BCHEMAOBMAOACYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275501-B1 | PROCESS FOR THE PREPARATION OF (Z)-2-(2-ARYLETHENYL)-ARYLCARBOXYLIC ACIDS | BASF Aktiengesellschaft (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4857658-A | Preparation of (Z)-2-(2-arylethenyl)arylcarboxylic acids | BASF AKTIENGESELLSCHAFT (DE) | 1989-08-15 | — | — | US | disclosed |
| EP-0275501-A1 | Process for the preparation of (Z)-2-(2-arylethenyl)-arylcarboxylic acids | BASF Aktiengesellschaft (DE) | 1988-07-27 | — | — | EP | disclosed |