Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27144018 | 0.81 | TSHR (0.70) | TSHRGAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7547745 | 0.81 | SMN1; SMN2 (0.71) | TSHRGAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6361102 | 0.80 | KMT2A (0.57) | ALDH1A1L3MBTL1TDP1LMNAMAPK1 | |
| SCHEMBL19388071 | 0.79 | POLB (0.68) | TSHRGAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11718177 | 0.79 | TSHR (0.68) | TSHRGAAKDM4EHSD17B10HPGD | |
| SCHEMBL31656350 | 0.79 | TSHR (0.68) | TSHRGAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL14818749 | 0.79 | TSHR (0.68) | TSHRGAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1116453 | 0.79 | LMNA (0.58) | ALDH1A1L3MBTL1TDP1LMNAMAPK1 | |
| SCHEMBL5360905 | 0.78 | L3MBTL1 (0.58) | ALDH1A1L3MBTL1TDP1HPGDLMNA | |
| SCHEMBL1189089 | 0.78 | HTT (0.55) | GAAALDH1A1HSD17B10L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777756-B | Heteroaryl compound and its application in drug | 广东东阳光药业有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-105777756-A | Heteroaryl compound and application thereof in medicines | 广东东阳光药业有限公司 | 2016-07-20 | — | — | CN | disclosed |