Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | IGF1R | P08069 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | ESRRB | O95718 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886091 | 0.81 | KDM4E (0.50) | KMT2AKDM4EMAPTALDH1A1GAA | |
| SCHEMBL31252540 | 0.79 | AKR1C3 (0.57) | AKR1C3USP2KMT2AKDM4EMAPT | |
| SCHEMBL175497 | 0.79 | MAPT (0.59) | USP2KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL1235260 | 0.79 | KDM4E (0.59) | AKR1C3USP2KMT2AKDM4EMAPT | |
| SCHEMBL16635950 | 0.76 | AKR1C3 (0.44) | AKR1C3USP2KMT2AKDM4EMAPT | |
| SCHEMBL23705658 | 0.75 | KMT2A (0.53) | AKR1C3USP2KMT2AKDM4EMAPT | |
| SCHEMBL382079 | 0.75 | KMT2A (0.58) | AKR1C3USP2KMT2AKDM4EMAPT | |
| SCHEMBL1169284 | 0.75 | KDM4E (0.74) | USP2KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL19402 | 0.74 | ALDH1A1 (0.63) | AKR1C3KMT2AKDM4EMAPTALDH1A1 | |
| Methyl Alcohol SCHEMBL10664077 | 0.74 | KMT2A (0.57) | AKR1C3USP2KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777756-A | Heteroaryl compound and application thereof in medicines | 广东东阳光药业有限公司 | 2016-07-20 | — | — | CN | disclosed |