SCHEMBL5886091

SCHEMBL5886091

Oc1ccc(N2CCS(O)(O)CC2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.50
MAPT P10636 3/20 0.50
ALDH1A1 P00352 3/20 0.50
PKM P14618 1/20 0.50
GAA P10253 3/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
DRD4 P21917 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
LMNA P02545 2/20 0.42
ME2 P23368 4/20 0.40
ME1 P48163 4/20 0.40
ME3 Q16798 4/20 0.40
DRD2 P14416 1/20 0.40
DRD3 P35462 1/20 0.40
CTSL P07711 1/20 0.39
CTSB P07858 1/20 0.39
GFER P55789 1/20 0.39
CA12 O43570 2/20 0.38
CA2 P00918 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7041242 0.81 MAPT (0.68) KDM4EMAPTALDH1A1PKMGAA
SCHEMBL175497 0.81 MAPT (0.59) KDM4EMAPTALDH1A1GAAMEN1
SCHEMBL5886084 0.81 KDM4E (0.65) KDM4EMAPTALDH1A1PKMGAA
SCHEMBL3043144 0.77 ALDH1A1 (0.57) KDM4EMAPTALDH1A1PKMGAA
SCHEMBL657027 0.77 ALDH1A1 (0.57) KDM4EMAPTALDH1A1PKMGAA
SCHEMBL1169284 0.76 KDM4E (0.74) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL526167 0.76 ALDH1A1 (0.63) KDM4EMAPTALDH1A1PKMGAA
SCHEMBL23701478 0.75 HSP90AA1 (0.62) KDM4EALDH1A1PKMTDP1LMNA
SCHEMBL19771741 0.75 KDM4E (0.57) KDM4EMAPTALDH1A1PKMGAA
SCHEMBL7106841 0.75 KDM4E (0.61) KDM4EMAPTALDH1A1PKMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7090969-B1 Coupler and image dye light-stabilizing systems EASTMAN KODAK COMPANY (US) 2006-08-15 US disclosed
US-5780625-A STABILIZERS FOR MAGENTA COUPLERS IN COLOR PHOTOGRAPHY RECORDING MATERIALS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-07-14 US disclosed