Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.48 |
| ▸ | SYK | P43405 | 4/20 | 0.47 |
| ▸ | JAK2 | O60674 | 8/20 | 0.44 |
| ▸ | JAK1 | P23458 | 8/20 | 0.44 |
| ▸ | JAK3 | P52333 | 8/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29644283 | 0.81 | MAP2K1 (0.57) | ADORA2AMEN1KMT2A | |
| SCHEMBL26979129 | 0.81 | MAP2K1 (0.57) | ADORA2AMEN1KMT2A | |
| SCHEMBL7024233 | 0.80 | ADORA2A (0.50) | ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL3554174 | 0.80 | ADORA2A (0.56) | ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL20769722 | 0.78 | ADORA2A (0.46) | ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL7025897 | 0.76 | ADORA2A (0.52) | ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL21676262 | 0.75 | TSHR (0.43) | — | |
| SCHEMBL4239387 | 0.75 | ADORA2A (0.48) | ADORA2AADORA1MEN1KMT2A | |
| SCHEMBL25027560 | 0.74 | AR (0.50) | MEN1KMT2A | |
| SCHEMBL29363618 | 0.74 | AR (0.50) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777756-A | Heteroaryl compound and application thereof in medicines | 广东东阳光药业有限公司 | 2016-07-20 | — | — | CN | disclosed |