Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27988345 | 0.87 | MET (0.55) | NR4A2ALDH1A1CASP1HTTTP53 | |
| SCHEMBL2955790 | 0.86 | CYP3A4 (0.59) | NR4A2ALDH1A1MEN1CASP1CASP7 | |
| SCHEMBL19263937 | 0.83 | NR4A2 (0.51) | NR4A2ALDH1A1MEN1CASP1CASP7 | |
| SCHEMBL317870 | 0.80 | NR4A2 (1.00) | NR4A2ALDH1A1MEN1CASP1CASP7 | |
| SCHEMBL29393522 | 0.80 | NR4A2 (1.00) | NR4A2ALDH1A1MEN1CASP1CASP7 | |
| SCHEMBL8918269 | 0.80 | NR4A2 (0.51) | NR4A2ALDH1A1MEN1CASP1CASP7 | |
| SCHEMBL9447104 | 0.79 | NR4A2 (0.58) | NR4A2ALDH1A1MEN1CASP1CASP7 | |
| SCHEMBL27969047 | 0.78 | CYP3A4 (0.76) | NR4A2ALDH1A1MEN1CASP1CASP7 | |
| SCHEMBL29096114 | 0.78 | NR4A2 (0.96) | NR4A2ALDH1A1MEN1CASP1CASP7 | |
| Hydrochloric Acid SCHEMBL30899592 | 0.78 | NR4A2 (0.96) | NR4A2ALDH1A1MEN1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104039798-B | There is thieno [3, the 2-d] pyrimidine derivatives of protein kinase inhibiting activity | 韩美药品株式会社 | 2016-08-24 | — | — | CN | disclosed |