Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177149 | 0.85 | NR4A2 (0.55) | NR4A2ALDH1A1HTTCASP1MEN1 | |
| SCHEMBL1496327 | 0.85 | NPC1 (0.57) | ALDH1A1HTTCASP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2472036 | 0.83 | NPC1 (0.55) | ALDH1A1HTTCASP1TP53RAB9A | |
| SCHEMBL6598156 | 0.81 | ALDH1A1 (0.53) | NR4A2ALDH1A1HTTCASP1MEN1 | |
| SCHEMBL464410 | 0.81 | ALDH1A1 (0.58) | NR4A2ALDH1A1HTTCASP1MEN1 | |
| SCHEMBL203509 | 0.81 | HTT (0.58) | NR4A2ALDH1A1HTTCASP1MEN1 | |
| SCHEMBL2865593 | 0.81 | ALDH1A1 (0.58) | NR4A2ALDH1A1HTTCASP1MEN1 | |
| SCHEMBL3821378 | 0.81 | ALDH1A1 (0.53) | NR4A2ALDH1A1HTTCASP1MEN1 | |
| SCHEMBL30647093 | 0.81 | HTT (0.58) | NR4A2ALDH1A1HTTCASP1MEN1 | |
| SCHEMBL1495700 | 0.81 | ALDH1A1 (0.53) | NR4A2ALDH1A1HTTCASP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |