Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.59 |
| ▸ | F3 | P13726 | 1/20 | 0.59 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.59 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.59 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.59 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.59 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.59 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Coumarin SCHEMBL14744008 | 0.84 | CA12 (0.67) | ALDH1A1HSD17B10HPGDCA12CA9 | |
| Coumarin SCHEMBL23929067 | 0.81 | CA12 (0.77) | ALDH1A1HSD17B10HPGDCA12CA9 | |
| Niacinamide SCHEMBL2926 | 0.77 | — | — | |
| Niacinamide SCHEMBL29624874 | 0.77 | — | — | |
| Niacinamide SCHEMBL19978192 | 0.77 | — | — | |
| Niacinamide SCHEMBL460466 | 0.77 | F7 (1.00) | F7F3SARM1SIRT2SIRT6 | |
| Coumarin SCHEMBL11798389 | 0.76 | CA12 (0.74) | ALDH1A1HSD17B10HPGDCA12CA9 | |
| Coumarin SCHEMBL28141892 | 0.76 | CA12 (0.74) | ALDH1A1HSD17B10HPGDCA12CA9 | |
| Coumarin SCHEMBL28679217 | 0.76 | CA12 (0.80) | ALDH1A1HSD17B10HPGDCA12CA9 | |
| Benzamide SCHEMBL594793 | 0.76 | F7 (0.88) | F7F3SARM1SIRT2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777729-A | Coumarin amides compound as well as preparation method and application of coumarin amides compound | 浙江工业大学 | 2016-07-20 | — | — | CN | disclosed |