Coumarin

Coumarin

SCHEMBL23929067

NC(=O)O.O=c1ccc2ccccc2o1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 8/20 0.77
CA9 Q16790 8/20 0.77
CA1 P00915 4/20 0.77
CA3 P07451 3/20 0.77
CA4 P22748 3/20 0.77
CA5A P35218 3/20 0.77
CA7 P43166 3/20 0.77
CA14 Q9ULX7 3/20 0.77
CA5B Q9Y2D0 3/20 0.77
MCL1 Q07820 3/20 0.77
CA2 P00918 2/20 0.77
TDP1 Q9NUW8 2/20 0.77
CA6 P23280 2/20 0.77
LMNA P02545 1/20 0.77
SOST Q9BQB4 1/20 0.77
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
HPGD P15428 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
PGR P06401 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumarin SCHEMBL1090505 0.92 CA12 (0.83) CA12CA9CA1CA3CA4
Coumarin SCHEMBL25431834 0.92 CA12 (0.91) CA12CA9CA1CA3CA4
Coumarin SCHEMBL19183240 0.90 CA12 (0.95) CA12CA9CA1CA3CA4
SCHEMBL7358531 0.90 CA12 (0.95) CA12CA9CA1CA3CA4
Coumarin SCHEMBL14744008 0.90 CA12 (0.67) CA12CA9CA1CA3CA4
Coumarin SCHEMBL29078087 0.89 CA12 (0.77) CA12CA9CA1CA3CA4
Coumarin SCHEMBL314829 0.89 CA9 (0.77) CA12CA9CA1CA3CA4
Coumarin SCHEMBL28052953 0.88 CA12 (0.91) CA12CA9CA1CA3CA4
Coumarin SCHEMBL7106473 0.88 CA12 (0.91) CA12CA9CA1CA3CA4
Coumarin SCHEMBL3441294 0.88 CA12 (1.00) CA12CA9CA1CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12419956-B2 Controlled drug release system of photoresponsive nanocarriers, methods of making and using thereof THE UNIVERSITY OF HONG KONG (CN) 2025-09-23 US disclosed
CN-115427031-B Controlled drug release systems of light responsive nanocarriers, methods of making and using the same 香港大学 2024-11-19 CN disclosed
US-20230124487-A1 A CONTROLLED DRUG RELEASE SYSTEM OF PHOTORESPONSIVE NANOCARRIERS, METHODS OF MAKING AND USING THEREOF THE UNIVERSITY OF HONG KONG (CN) 2023-04-20 US disclosed
EP-4138816-A1 A CONTROLLED DRUG RELEASE SYSTEM OF PHOTORESPONSIVE NANOCARRIERS, METHODS OF MAKING AND USING THEREOF The University of Hong Kong (CN) 2023-03-01 EP disclosed
CN-115427031-A Controlled drug release system of photoresponsive nanocarrier, methods of making and using the same 香港大学 2022-12-02 CN disclosed
WO-2021213089-A1 A CONTROLLED DRUG RELEASE SYSTEM OF PHOTORESPONSIVE NANOCARRIERS, METHODS OF MAKING AND USING THEREOF THE UNIVERSITY OF HONG KONG (CN) 2021-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12419956-B2 Controlled drug release system of photoresponsive nanocarriers, methods of making and using thereof ABCB1, STRA6, LIPA CA12 2594/4885CA9 1935/4885CA1 4374/4885
US-20230124487-A1 A CONTROLLED DRUG RELEASE SYSTEM OF PHOTORESPONSIVE NANOCARRIERS, METHODS OF MAKING AND USING THEREOF GHRHR, ABCB1, GRPR CA12 2665/4885CA9 1964/4885CA1 4361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.