SCHEMBL28089748

SCHEMBL28089748

CCC(=O)C(C)S(=O)(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
PSIP1 O75475 1/20 0.45
MMP1 P03956 3/20 0.43
MMP7 P09237 3/20 0.43
MMP12 P39900 3/20 0.43
MMP13 P45452 3/20 0.43
ACE P12821 2/20 0.43
ATM Q13315 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
LARS1 Q9P2J5 1/20 0.40
TSHR P16473 2/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1200588 0.80 CA1 (0.53) CA12CA1CA2CA9PSIP1
SCHEMBL12587896 0.79 ATM (0.55) HSD11B1CA12CA1CA2CA9
SCHEMBL16884985 0.79 CA12 (0.51) HSD11B1CA12CA1CA2CA9
SCHEMBL13282574 0.78 CA12 (0.43) HSD11B1CA12CA1CA2CA9
SCHEMBL1161572 0.77 CA12 (0.54) CA12CA1CA2CA9SMN1; SMN2
SCHEMBL8959071 0.77 CA2 (0.54) CA12CA1CA2CA9MMP1
SCHEMBL27933104 0.77 CA12 (0.50) HSD11B1CA12CA1CA2CA9
SCHEMBL11329369 0.76 CA1 (0.49) CA12CA1CA2CA9PSIP1
SCHEMBL25705135 0.76 HSD11B1 (0.44) HSD11B1PSIP1MMP1MMP7MMP12
SCHEMBL13282474 0.76 CA12 (0.41) HSD11B1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105873986-B Metal nanoparticle protects polymer and colloidal metal solution and the method for preparing it DIC株式会社 2019-04-30 CN disclosed
CN-106496367-A Catalytic component and its preparation and application for olefinic polymerization 中国石油化工股份有限公司 2017-03-15 CN disclosed
CN-105873986-A Metal nanoparticle-protecting polymer and metal colloidal solution, and method for producing same DIC株式会社 2016-08-17 CN disclosed