Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089990 | 1.00 | HDAC4 (0.58) | HDAC4MEF2DALDH1A1KDM4ENPC1 | |
| SCHEMBL5431353 | 0.85 | HDAC4 (0.53) | HDAC4MEF2DALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL44580 | 0.84 | PTGS2 (0.59) | HDAC4MEF2DALDH1A1KDM4EPTGS1 | |
| SCHEMBL44581 | 0.84 | PTGS2 (0.59) | HDAC4MEF2DALDH1A1KDM4EPTGS1 | |
| SCHEMBL5431345 | 0.84 | HDAC4 (0.60) | HDAC4MEF2DALDH1A1KDM4EHPGD | |
| SCHEMBL5431348 | 0.84 | HDAC4 (0.60) | HDAC4MEF2DALDH1A1KDM4EHPGD | |
| SCHEMBL2546761 | 0.84 | HDAC4 (0.56) | HDAC4MEF2DALDH1A1KDM4ENPC1 | |
| SCHEMBL2546760 | 0.84 | HDAC4 (0.56) | HDAC4MEF2DALDH1A1KDM4ENPC1 | |
| SCHEMBL15026335 | 0.80 | NPSR1 (0.49) | HDAC4MEF2DALDH1A1KDM4EPTGS1 | |
| SCHEMBL19313214 | 0.80 | NPSR1 (0.49) | HDAC4MEF2DALDH1A1KDM4EPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814018-B | New carbamide compounds, preparation method and its usage | 中国人民解放军军事医学科学院毒物药物研究所 | 2018-03-20 | — | — | CN | claimed |
| CN-105814018-A | New urea compound, manufacturing method and application thereof | 中国人民解放军军事医学科学院毒物药物研究所 | 2016-07-27 | — | — | CN | claimed |
| CN-105814018-B | New carbamide compounds, preparation method and its usage | 中国人民解放军军事医学科学院毒物药物研究所 | 2018-03-20 | — | — | CN | disclosed |
| CN-105814018-A | New urea compound, manufacturing method and application thereof | 中国人民解放军军事医学科学院毒物药物研究所 | 2016-07-27 | — | — | CN | disclosed |