SCHEMBL28090688

SCHEMBL28090688

CO[Si](COC(=O)C(C)(C)C)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.38
ELANE P08246 4/20 0.34
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
BTN3A1 O00481 2/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28262398 0.92 PRKCA (0.34) PRKCAELANEPOLBGAANPSR1
SCHEMBL12540627 0.83
SCHEMBL20143349 0.81 CYP4F2 (0.34)
SCHEMBL15315078 0.80 PRKCA (0.37) PRKCAELANEPOLBGAANPSR1
SCHEMBL28137287 0.80 PRKCA (0.37) PRKCAELANEPOLBGAANPSR1
SCHEMBL12610865 0.78 PRKCA (0.40) PRKCAELANEPOLBGAANPSR1
SCHEMBL28071214 0.78 PRKCA (0.36) PRKCAPOLBGAANPSR1
SCHEMBL28205699 0.76 PRKCA (0.41) PRKCAELANEPOLBGAANPSR1
SCHEMBL28302453 0.76 TSHR (0.43) MAPT
SCHEMBL16558885 0.74 NAAA (0.40) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110452621-A A kind of bonding silane coupling agent and preparation method thereof for solid tire reflective strip NINGBO JEEAO CHUANGYI NEW MAT CO LTD 2019-11-15 CN claimed
CN-110205087-A Heat cure no-solvent type organosilicon conductive adhesive 郝建强 2019-09-06 CN disclosed
CN-110087905-A reinforced rubber composition 米其林集团总公司 2019-08-02 CN disclosed
CN-106752954-B CCB high sealing water-repellent paint 广东鼎新高新科技股份有限公司 2019-04-02 CN disclosed
CN-108359100-A A kind of dynamic covalent polymer and its application 翁秋梅 2018-08-03 CN disclosed
CN-107923176-A Self-sealing article comprising an elastic porous layer 3M创新有限公司 2018-04-17 CN disclosed
CN-104797232-B Curable composition for dental applications and dental flowable composite resin 可乐丽则武齿科株式会社 2017-11-07 CN disclosed
CN-106752954-A CCB high sealing water-repellent paints 广东鼎新高新科技股份有限公司 2017-05-31 CN disclosed
CN-104609759-B Additive capable of improving bending strength and tensile strength of cement base material and its preparation method 江苏苏博特新材料股份有限公司 2017-04-12 CN disclosed
CN-104870395-B Use of hybrid copolymers as protective colloids for polymers 瓦克化学股份公司 2016-11-23 CN disclosed
CN-103718091-B Silicon-containing liquid crystal aligning agent, liquid crystal orientation film and liquid crystal display cells 日产化学工业株式会社 2016-08-31 CN disclosed