Pyrrole

Pyrrole

SCHEMBL28091046

Brc1cc2ccccc2[nH]1.c1cc[nH]c1

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.46
AOC3 Q16853 2/20 0.45
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
FLT3 P36888 1/20 0.41
CYP2A6 P11509 1/20 0.41
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 3/20 0.41
MAPT P10636 2/20 0.41
DAO P14920 2/20 0.40
HPGD P15428 1/20 0.40
SRD5A2 P31213 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
BRD4 O60885 1/20 0.40
DDO Q99489 1/20 0.40
GAA P10253 1/20 0.40
MAPK1 P28482 1/20 0.40
HRH4 Q9H3N8 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29425617 0.89 AOC3 (0.54) LOXL2AOC3NPC1RAB9AFLT3
SCHEMBL261138 0.89 AOC3 (0.54) LOXL2AOC3NPC1RAB9AFLT3
SCHEMBL27618858 0.89 AOC3 (0.54) LOXL2AOC3NPC1RAB9AFLT3
SCHEMBL3591265 0.89 AOC3 (0.54) LOXL2AOC3NPC1RAB9AFLT3
SCHEMBL6824703 0.87 AOC3 (0.52) LOXL2AOC3NPC1RAB9AFLT3
Sulfamide SCHEMBL27827775 0.78 CA2 (0.59) LOXL2AOC3NPC1RAB9AFLT3
Pyrrole SCHEMBL27718192 0.76 AOC3 (0.80) LOXL2AOC3NPC1RAB9AFLT3
Pyrrole SCHEMBL412879 0.76 AOC3 (0.80) LOXL2AOC3NPC1RAB9AFLT3
Pyrrole SCHEMBL28184710 0.76 DAO (0.48) LOXL2AOC3NPC1RAB9AFLT3
Formic Acid Methyl Ester SCHEMBL27945794 0.74 CYP2A6 (0.49) AOC3NPC1RAB9AFLT3CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104341584-B Poly-3,8-bis-indoles pyrroles and its preparation method and application 华南理工大学 2016-08-17 CN claimed
CN-104341584-B Poly-3,8-bis-indoles pyrroles and its preparation method and application 华南理工大学 2016-08-17 CN disclosed