Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | DDO | Q99489 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29425617 | 1.00 | AOC3 (0.54) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL261138 | 1.00 | AOC3 (0.54) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL27618858 | 1.00 | AOC3 (0.54) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL6824703 | 0.98 | AOC3 (0.52) | AOC3NPC1RAB9ALOXL2FLT3 | |
| Pyrrole SCHEMBL28091046 | 0.89 | LOXL2 (0.46) | AOC3NPC1RAB9ALOXL2FLT3 | |
| Sulfamide SCHEMBL27827775 | 0.88 | CA2 (0.59) | AOC3NPC1RAB9ALOXL2FLT3 | |
| Formic Acid Methyl Ester SCHEMBL27945794 | 0.83 | CYP2A6 (0.49) | AOC3NPC1RAB9AFLT3CYP2A6 | |
| Quinoline SCHEMBL28065955 | 0.82 | ALDH1A1 (0.57) | AOC3NPC1RAB9AKDM4EMAPT | |
| SCHEMBL30010158 | 0.76 | ALDH1A1 (0.45) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL28159595 | 0.74 | FGFR1 (0.49) | NPC1RAB9AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076365-B2 | Viral polymerase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-13 | — | — | US | disclosed |
| US-20100168098-A1 | Viral Polymerase Inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-01 | — | — | US | disclosed |
| EP-1915378-A4 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2009-07-22 | — | — | EP | disclosed |
| EP-1915378-A1 | VIRAL POLYMERASE INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007019674-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168098-A1 | Viral Polymerase Inhibitors | POLR2A, POLR1E, POLR2E | AOC3 2706/4885NPC1 751/4885RAB9A 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.