Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNG | P07510 | 1/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27902048 | 0.82 | KCNN4 (0.43) | MEN1KMT2AKCNN4AKR1C3AKR1C2 | |
| SCHEMBL6967423 | 0.82 | KCNN4 (0.43) | MEN1KMT2AKCNN4AKR1C3AKR1C2 | |
| SCHEMBL2460935 | 0.78 | MEN1 (0.38) | MEN1KMT2AKCNN4AKR1C3AKR1C2 | |
| SCHEMBL3950869 | 0.77 | ESR1 (0.44) | KCNN4AKR1C3AKR1C2CHRM3HDAC3 | |
| SCHEMBL828570 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2AKCNN4AKR1C3AKR1C2 | |
| SCHEMBL9576388 | 0.77 | TSHR (0.48) | KCNN4AKR1C3AKR1C2CHRM3HDAC3 | |
| SCHEMBL4473460 | 0.77 | KCNN4 (0.41) | KMT2AKCNN4AKR1C3AKR1C2CHRM3 | |
| SCHEMBL28202239 | 0.75 | KCNN4 (0.39) | MEN1KMT2AKCNN4AKR1C3AKR1C2 | |
| SCHEMBL21229776 | 0.74 | KCNN4 (0.45) | MEN1KMT2AKCNN4AKR1C3AKR1C2 | |
| SCHEMBL6961485 | 0.74 | CHRM3 (0.42) | MEN1KMT2AKCNN4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023142153-A1 | CARBONYL REDUCTASE AND USE THEREOF | 山东寰酶生物制药有限公司 | 2023-08-03 | — | — | WO | disclosed |
| CN-109439696-A | A method of preparing the chloro- 1-(3,4- difluorophenyl of (R) -2-) ethyl alcohol | 尚科生物医药（上海）有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-105969757-A | Enzyme immobilization method and application | 中国科学院成都生物研究所 | 2016-09-28 | — | — | CN | disclosed |