Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.49 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.49 |
| ▸ | RXRG | P48443 | 2/20 | 0.49 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544608 | 0.82 | MRGPRX4 (0.50) | MRGPRX4RXRARXRBRXRGLIPE | |
| SCHEMBL4770223 | 0.80 | LIPE (0.46) | MRGPRX4LIPELMNACYP1A2PTGS1 | |
| SCHEMBL30711914 | 0.79 | SMPD1 (0.56) | MRGPRX4RXRALIPELMNAHDAC6 | |
| SCHEMBL20756090 | 0.78 | RXRA (0.54) | MRGPRX4RXRARXRBRXRGLIPE | |
| SCHEMBL20482536 | 0.78 | RXRA (0.56) | MRGPRX4RXRARXRBRXRG | |
| SCHEMBL16548414 | 0.77 | MRGPRX4 (0.53) | MRGPRX4RXRARXRBRXRGLIPE | |
| SCHEMBL544693 | 0.77 | MRGPRX4 (0.50) | MRGPRX4RXRARXRBRXRGAR | |
| SCHEMBL544134 | 0.77 | MRGPRX4 (0.50) | MRGPRX4RXRARXRBRXRG | |
| SCHEMBL849231 | 0.76 | RXRA (0.72) | MRGPRX4RXRARXRBRXRGPTGER1 | |
| SCHEMBL20482946 | 0.75 | RXRA (0.52) | MRGPRX4RXRARXRBRXRGAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029072-A | Heterocyclic compounds and methods of use | 麦迪韦逊技术股份有限公司 | 2016-10-12 | — | — | CN | disclosed |