Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.84 |
| ▸ | LMNA | P02545 | 1/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.84 |
| ▸ | TSHR | P16473 | 1/20 | 0.84 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | KDM5A | P29375 | 4/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Protionamide SCHEMBL74572 | 0.92 | KDM4E (1.00) | KDM4ELMNACYP3A4TSHRCYP1A2 | |
| Protionamide SCHEMBL30271512 | 0.92 | KDM4E (1.00) | KDM4ELMNACYP3A4TSHRCYP1A2 | |
| SCHEMBL3634347 | 0.84 | KDM4E (0.59) | KDM4ELMNACYP3A4TSHRCYP1A2 | |
| Ethionamide SCHEMBL12264086 | 0.83 | CYP1A2 (1.00) | KDM4ELMNACYP3A4TSHRCYP1A2 | |
| Ethionamide SCHEMBL12264091 | 0.83 | CYP1A2 (1.00) | KDM4ELMNACYP3A4TSHRCYP1A2 | |
| Ethionamide SCHEMBL12264085 | 0.83 | CYP1A2 (1.00) | KDM4ELMNACYP3A4TSHRCYP1A2 | |
| Ethionamide SCHEMBL12264093 | 0.83 | CYP1A2 (1.00) | KDM4ELMNACYP3A4TSHRCYP1A2 | |
| Ethionamide SCHEMBL27007 | 0.83 | CYP1A2 (1.00) | KDM4ELMNACYP3A4TSHRCYP1A2 | |
| Ethionamide SCHEMBL12264095 | 0.83 | CYP1A2 (1.00) | KDM4ELMNACYP3A4TSHRCYP1A2 | |
| Ethionamide SCHEMBL12264090 | 0.83 | CYP1A2 (1.00) | KDM4ELMNACYP3A4TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029072-A | Heterocyclic compounds and methods of use | 麦迪韦逊技术股份有限公司 | 2016-10-12 | — | — | CN | disclosed |