Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL561018 | 0.86 | CYP19A1 (0.48) | SMN1; SMN2CYP3A4TSHRCYP19A1TTR | |
| SCHEMBL716259 | 0.86 | CYP19A1 (0.54) | SMN1; SMN2CYP3A4TSHRCYP19A1TTR | |
| SCHEMBL28092839 | 0.81 | CYP19A1 (0.40) | SMN1; SMN2CYP3A4TSHRCYP19A1HTT | |
| SCHEMBL16951824 | 0.81 | HTT (0.48) | SMN1; SMN2CYP3A4TSHRCYP19A1HTT | |
| SCHEMBL2671826 | 0.79 | CYP19A1 (0.62) | SMN1; SMN2CYP3A4TSHRCYP19A1TTR | |
| SCHEMBL31347504 | 0.78 | ACHE (0.54) | SMN1; SMN2TSHRCYP19A1TTRHTT | |
| SCHEMBL11025268 | 0.78 | ACHE (0.54) | SMN1; SMN2TSHRCYP19A1TTRHTT | |
| SCHEMBL30319435 | 0.78 | TSHR (0.56) | SMN1; SMN2CYP3A4TSHRCYP19A1TTR | |
| SCHEMBL18407603 | 0.78 | TSHR (0.56) | SMN1; SMN2CYP3A4TSHRCYP19A1TTR | |
| SCHEMBL16954441 | 0.78 | ALOX5 (0.45) | SMN1; SMN2CYP3A4TSHRCYP19A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029651-A | Urea derivatives as kinase inhibitors | 瑞斯比维特有限公司 | 2016-10-12 | — | — | CN | disclosed |