Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584625 | 0.71 | ALDH1A1 (0.42) | PDE4BSLC6A3MEN1KMT2AKCNH2 | |
| SCHEMBL3644937 | 0.71 | GAA (0.38) | GAAMAPTBRD4HTTHDAC1 | |
| SCHEMBL19260079 | 0.70 | MAPT (0.47) | GAAMAPTBRD4HTTHDAC1 | |
| SCHEMBL17489171 | 0.69 | PDE4B (0.48) | GAAMAPTBRD4HTTHDAC1 | |
| SCHEMBL28858185 | 0.69 | GAA (0.46) | GAAMAPTBRD4HTTHDAC1 | |
| SCHEMBL10141560 | 0.67 | SLC6A3 (0.35) | SLC6A3KCNH2OPRD1 | |
| SCHEMBL16260559 | 0.66 | GAA (0.46) | GAAMAPTBRD4HTTHDAC1 | |
| SCHEMBL3644938 | 0.66 | GAA (0.42) | GAAMAPTBRD4HTTHDAC1 | |
| SCHEMBL28416242 | 0.65 | — | — | |
| SCHEMBL30542099 | 0.64 | GAA (0.41) | GAAMAPTBRD4HTTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980386-A | Pyrazolo compounds and uses thereof | 基因泰克公司 | 2016-09-28 | — | — | CN | disclosed |