Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.93 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.93 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.51 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL3260 | 0.97 | CYP3A4 (1.00) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| D-Histidine SCHEMBL288043 | 0.97 | CYP3A4 (1.00) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Histidine SCHEMBL388560 | 0.97 | CYP3A4 (1.00) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Histidine SCHEMBL30852263 | 0.97 | CYP3A4 (1.00) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Histidine SCHEMBL19974306 | 0.97 | CYP3A4 (1.00) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Histidine SCHEMBL28071764 | 0.97 | CYP3A4 (1.00) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Histidine SCHEMBL137600 | 0.97 | CYP3A4 (1.00) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Histidine SCHEMBL27738090 | 0.95 | CYP3A4 (0.90) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Histidine SCHEMBL25357958 | 0.95 | CYP3A4 (0.97) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Histidine SCHEMBL25362582 | 0.95 | CYP3A4 (0.97) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104114159-B | Polymeric excipients for particle lyophilization or freezing | 阿布拉科斯生物科学有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-110022902-A | Conjugates comprising a GLP-1/glucagon dual agonist, a linker and hyaluronic acid | 赛诺菲 | 2019-07-16 | — | — | CN | disclosed |
| CN-104998269-B | For stablizing the preparation containing protein useful composition and method | 弗·哈夫曼-拉罗切有限公司 | 2019-06-11 | — | — | CN | disclosed |
| CN-109771377-A | Polymeric excipients for particle lyophilization or freezing | 阿布拉科斯生物科学有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-104740631-B | The preparation of single domain antigen-binding molecule | 阿布林克斯公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109195629-A | Influenza antibody molecular preparation | 威特拉公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-108883162-A | METHODS AND COMPOSITIONS FOR CNS DELIVERY OF ARYLSULFATASE A | 夏尔人类遗传性治疗公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-104768580-B | Liquid formulations comprising GM-CSF neutralizing compounds | 安进研发（慕尼黑）股份有限公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-108602881-A | ANTI-FACTOR D ANTIBODY FORMULATIONS | 豪夫迈·罗氏有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108472368-A | Novel anti-UPK 1B antibodies and methods of use | 艾伯维施特姆森特克斯有限责任公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-107949391-A | Compositions for fecal flora transplantation and methods for making and using them and devices for delivering them | 克雷斯顿沃控股公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-107750168-A | Prodrugs comprising G L P1/glucagon dual agonist linker hyaluronic acid conjugates | 赛诺菲 | 2018-03-02 | — | — | CN | disclosed |
| CN-107073113-A | Anti- IL 7R antibody compositions | 辉瑞大药厂 | 2017-08-18 | — | — | CN | disclosed |
| CN-106983862-A | For the useful composition of the stable preparation containing protein and method | 弗·哈夫曼-拉罗切有限公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-106659785-A | LIQUID FORMULATION COMPRISING GM-CSF NEUTRALIZING COMPOUND | 武田有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-103987405-B | anti-PD-L1 antibodies and uses thereof | 默克专利股份公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-103906766-B | Anti- CD83 agonist antibody is used for treating the purposes of autoimmune disease | 弗·哈夫曼-拉罗切有限公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-103124564-B | Compositions and methods useful for stabilizing protein-containing formulations | 弗·哈夫曼-拉罗切有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105992584-A | Compositions and methods for atmospheric spray freeze drying | 喷雾剂治疗学有限公司 | 2016-10-05 | — | — | CN | disclosed |
| CN-103068367-B | Compositions and methods comprising alkylglycosides for stabilizing protein-containing formulations | 弗·哈夫曼-拉罗切有限公司 | 2016-09-07 | — | — | CN | disclosed |