Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520490 | 0.82 | TSHR (0.33) | KDM4ELMNAALDH1A1TDP1MAPT | |
| SCHEMBL516881 | 0.81 | ALDH1A1 (0.49) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL11875422 | 0.81 | ALDH1A1 (0.49) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8645713 | 0.80 | KDM4E (0.59) | KDM4ELMNAALDH1A1TDP1MAPT | |
| Quinoline SCHEMBL28320577 | 0.76 | ALDH1A1 (0.55) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL9839797 | 0.75 | LMNA (0.57) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL27372062 | 0.73 | KDM4E (0.42) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8811771 | 0.73 | KDM4E (0.55) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL3176306 | 0.72 | KDM4E (0.49) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL546320 | 0.71 | MGAM (0.47) | KDM4ELMNAALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084867-A | Condensed ring compound | 豪夫迈·罗氏有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084870-A | Condensed ring compound | 豪夫迈·罗氏有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084866-A | Condensed ring compound | 豪夫迈·罗氏有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084868-A | Condensed ring compound | 豪夫迈·罗氏有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112105419-B | Condensed ring compound | 豪夫迈·罗氏有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-112105419-A | Fused ring compound | 豪夫迈·罗氏有限公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-107614498-A | Diaza benzofluoranthrene class compound | 哈药集团制药总厂 | 2018-01-19 | — | — | CN | disclosed |
| CN-105985333-A | Diaza-benzofluoranthene type compounds | 哈药集团技术中心 | 2016-10-05 | — | — | CN | disclosed |