Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.96 |
| ▸ | MEN1 | O00255 | 5/20 | 0.96 |
| ▸ | TP53 | P04637 | 4/20 | 0.96 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.96 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.96 |
| ▸ | LMNA | P02545 | 6/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.81 |
| ▸ | ESR1 | P03372 | 5/20 | 0.79 |
| ▸ | PGR | P06401 | 2/20 | 0.79 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.79 |
| ▸ | AR | P10275 | 2/20 | 0.79 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.79 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.79 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.79 |
| ▸ | ATM | Q13315 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Estradiol Propionate SCHEMBL26659949 | 0.98 | MAPT (1.00) | MAPTKMT2ACYP3A4MEN1TP53 | |
| Estradiol Propionate SCHEMBL30165166 | 0.98 | MAPT (1.00) | MAPTKMT2ACYP3A4MEN1TP53 | |
| Estradiol Propionate SCHEMBL480992 | 0.98 | MAPT (1.00) | MAPTKMT2ACYP3A4MEN1TP53 | |
| Estradiol Propionate SCHEMBL30384276 | 0.98 | MAPT (1.00) | MAPTKMT2ACYP3A4MEN1TP53 | |
| Estradiol Propionate SCHEMBL28092621 | 0.93 | MAPT (0.91) | MAPTKMT2ACYP3A4MEN1TP53 | |
| Estradiol Propionate SCHEMBL27583398 | 0.91 | MAPT (0.86) | MAPTKMT2ACYP3A4MEN1TP53 | |
| SCHEMBL9404746 | 0.90 | MAPT (0.89) | MAPTKMT2ACYP3A4MEN1TP53 | |
| SCHEMBL15081191 | 0.90 | LMNA (0.84) | MAPTKMT2ACYP3A4MEN1TP53 | |
| SCHEMBL19393249 | 0.90 | MAPT (0.89) | MAPTKMT2ACYP3A4MEN1TP53 | |
| SCHEMBL10653053 | 0.90 | MAPT (0.85) | MAPTKMT2ACYP3A4MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105992766-A | Pyrrolo [3,2-C ] pyridine derivatives as TLR inhibitors | 武田药品工业株式会社 | 2016-10-05 | — | — | CN | disclosed |