Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.55 |
| ▸ | CA9 | Q16790 | 10/20 | 0.55 |
| ▸ | CA1 | P00915 | 9/20 | 0.55 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11973731 | 0.82 | MAPT (0.52) | CA2CA9CA1STSGAA | |
| Hydrogen Sulfide SCHEMBL6129793 | 0.79 | KDM4E (0.49) | CA2CA9CA1STSGAA | |
| SCHEMBL28431308 | 0.79 | ELANE (0.42) | CA2CA9CA1STS | |
| SCHEMBL28431310 | 0.76 | KMT2A (0.33) | CA2CA9CA1STS | |
| SCHEMBL28871974 | 0.76 | KDM4E (0.33) | CA2CA9CA1GAA | |
| SCHEMBL19348578 | 0.73 | CA2 (0.75) | CA2CA9CA1STSGAA | |
| SCHEMBL3372383 | 0.72 | CA2 (0.52) | CA2CA9CA1STSGAA | |
| SCHEMBL2592444 | 0.71 | CA2 (0.50) | CA2CA9CA1STSGAA | |
| SCHEMBL11973138 | 0.71 | CA2 (0.46) | CA2CA9CA1STS | |
| SCHEMBL20582860 | 0.70 | KDM4E (0.56) | CA2CA9CA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105899509-B | Isopropyl triazolopyridine compounds | 伊莱利利公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-105899509-A | Isopropyl triazolopyridine compounds | 伊莱利利公司 | 2016-08-24 | — | — | CN | disclosed |