Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.50 |
| ▸ | CA9 | Q16790 | 10/20 | 0.50 |
| ▸ | CA1 | P00915 | 9/20 | 0.50 |
| ▸ | STS | P08842 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372383 | 0.98 | CA2 (0.52) | CA2CA9CA1STSALDH1A1 | |
| SCHEMBL9451267 | 0.82 | CA2 (0.61) | CA2CA9CA1STS | |
| SCHEMBL11973731 | 0.82 | MAPT (0.52) | CA2CA9CA1STSMEN1 | |
| SCHEMBL777548 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2AESR1 | |
| SCHEMBL29468655 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2AESR1 | |
| SCHEMBL6937363 | 0.78 | ALDH1A1 (0.45) | ALDH1A1LMNAMEN1KMT2AESR1 | |
| SCHEMBL30821607 | 0.78 | ALDH1A1 (0.45) | ALDH1A1LMNAMEN1KMT2AESR1 | |
| SCHEMBL2995397 | 0.77 | ALDH1A1 (0.44) | ALDH1A1LMNAMEN1KMT2AESR1 | |
| SCHEMBL28967200 | 0.77 | ELANE (0.59) | ALDH1A1LMNAMEN1KMT2AESR1 | |
| SCHEMBL777549 | 0.77 | SLC22A6 (0.46) | ALDH1A1LMNAMEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123135-A1 | Methods To Identify Modulators of TAS2R48 Receptors | GIVAUDAN SA (CH) | 2013-05-16 | — | — | US | disclosed |
| US-20130115624-A1 | Methods To Identify Modulators | GIVAUDAN S.A. (CH) | 2013-05-09 | — | — | US | disclosed |
| EP-2567231-A1 | METHODS TO IDENTIFY MODULATORS OF TAS2R4S RECEPTORS | Givaudan SA (CH) | 2013-03-13 | — | — | EP | disclosed |
| EP-2567229-A1 | METHODS TO IDENTIFY MODULATORS | Givaudan SA (CH) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138456-A1 | METHODS TO IDENTIFY MODULATORS OF TAS2R4S RECEPTORS | GIVAUDAN SA (CH) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011138455-A1 | METHODS TO IDENTIFY MODULATORS | GIVAUDAN SA (CH) | 2011-11-10 | — | — | WO | disclosed |