Pyriproxyfen

Pyriproxyfen

SCHEMBL28095441

CC(COc1ccc(Oc2ccccc2)cc1)Oc1ccccn1.NCC(O)c1ccc(O)cc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 3/20 0.42
SLC6A2 P23975 2/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
CYP2D6 P10635 1/20 0.42
DRD1 P21728 1/20 0.42
SLC6A4 P31645 1/20 0.42
CYP2C19 P33261 1/20 0.42
ADRA1A P35348 1/20 0.42
OPRM1 P35372 1/20 0.42
DRD3 P35462 1/20 0.42
SLC6A3 Q01959 1/20 0.42
KMT2A Q03164 1/20 0.42
KCNH2 Q12809 1/20 0.42
CDK1 P06493 1/20 0.42
TAAR1 Q96RJ0 2/20 0.42
HTR3A P46098 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyriproxyfen SCHEMBL29370858 0.84 LTA4H (0.45) LTA4HLMNAPTGS1
Pyriproxyfen SCHEMBL2355621 0.84 LTA4H (0.45) LTA4HLMNAPTGS1
Pyriproxyfen SCHEMBL26721 0.84 LTA4H (0.45) LTA4HLMNAPTGS1
Pyriproxyfen SCHEMBL8456790 0.84 LTA4H (0.45) LTA4HLMNAPTGS1
SCHEMBL9575826 0.84 SLC6A2 (0.42) HIF1ASLC6A2MEN1CYP1A2HTR1A
Pyriproxyfen SCHEMBL4048811 0.84 LTA4H (0.45) LTA4HLMNAPTGS1
Pyriproxyfen SCHEMBL29157105 0.83 LTA4H (0.44) HIF1AMEN1KMT2ATSHRKDM4E
Pyriproxyfen SCHEMBL28444353 0.83 LTA4H (0.44) LTA4HLMNAPTGS1
Pyriproxyfen SCHEMBL29062529 0.81 LTA4H (0.43) CYP2D6LTA4HLMNAPTGS1
Pyriproxyfen SCHEMBL25262618 0.81 LTA4H (0.41) LTA4HLMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104663674-B Fungicide compound and mixture 杜邦公司 2017-11-03 CN disclosed
CN-104311554-B Mesoionic pesticides 纳幕尔杜邦公司 2017-05-24 CN disclosed
CN-104540824-B The solid form of Pyridopyrimidine inner salt 杜邦公司 2017-03-29 CN disclosed
CN-103819470-B Mesoionic pesticides 杜邦公司 2016-08-24 CN disclosed