Pyriproxyfen

Pyriproxyfen

SCHEMBL4048811

C[C@@H](COc1ccc(Oc2ccccc2)cc1)Oc1ccccn1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.45
LMNA P02545 1/20 0.44
PTGS2 P35354 1/20 0.41
MAOA P21397 1/20 0.41
PTGS1 P23219 1/20 0.41
PLA2G2A P14555 1/20 0.39
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
XBP1 P17861 1/20 0.38
ADAMTS4 O75173 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyriproxyfen SCHEMBL29370858 1.00 LTA4H (0.45) LTA4HLMNAPTGS2MAOAPTGS1
Pyriproxyfen SCHEMBL26721 1.00 LTA4H (0.45) LTA4HLMNAPTGS2MAOAPTGS1
Pyriproxyfen SCHEMBL2355621 1.00 LTA4H (0.45) LTA4HLMNAPTGS2MAOAPTGS1
Pyriproxyfen SCHEMBL8456790 1.00 LTA4H (0.45) LTA4HLMNAPTGS2MAOAPTGS1
Pyriproxyfen SCHEMBL28444353 0.99 LTA4H (0.44) LTA4HLMNAPTGS2MAOAPTGS1
Pyriproxyfen SCHEMBL29157105 0.99 LTA4H (0.44) LTA4HLMNAPTGS2MAOAPTGS1
Pyriproxyfen SCHEMBL25262618 0.96 LTA4H (0.41) LTA4HLMNAPTGS2MAOAPTGS1
SCHEMBL9618194 0.94 LMNA (0.49) LMNAMAOAPTGS1POLBMAPT
Pyriproxyfen SCHEMBL29062529 0.93 LTA4H (0.43) LTA4HLMNAPTGS2MAOAPTGS1
SCHEMBL21984849 0.92 MEN1 (0.40) LTA4HLMNAPTGS2MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1380342-B1 COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST SUMITOMO CHEMICAL CO (JP) 2009-07-01 EP disclosed
EP-1989209-A2 ORGANIC COMPOUNDS Novartis AG (CH) 2008-11-12 EP disclosed
WO-2007096150-A2 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2007-08-30 WO disclosed
US-6995110-B2 Complex catalyst, process for producing the complex catalyst, and process for producing alcohol derivative with the complex catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-02-07 US disclosed
EP-1534684-A1 INDAZOLE-AMINOACETONITRILE DERIVATIVES HAVING SPECIAL PESTICIDAL ACTIVITY Novartis AG (CH) 2005-06-01 EP disclosed
US-20040077487-A1 Complex catalyst, process for producing the complex catalyst, and process for producing alchohol derivative with the complex catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-22 US disclosed
EP-1401277-A1 AMENOACETONITRILE COMPOUNDS FOR CONTROLLING ENDOPARASITES Novartis AG (CH) 2004-03-31 EP disclosed
EP-1392281-A2 ANTI-ENDOPARASITIC AMIDOACETONITRILS Novartis AG (CH) 2004-03-03 EP disclosed
EP-1380342-A1 COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2004-01-14 EP disclosed
WO-2003104202-A1 INDAZOLE-AMINOACETONITRILE DERIVATIVES HAVING SPECIAL PESTICIDAL ACTIVITY NOVARTIS AG (CH) 2003-12-18 WO disclosed
EP-1254135-A2 AMINOHETEROCYCLYLAMIDES AS PESTICIDES AND ANTIPARASITIC AGENTS Novartis AG (CH) 2002-11-06 EP disclosed
EP-1230239-A1 PESTICIDAL AMINOHETEROCYCLAMIDE COMPOUNDS Novartis AG (CH) 2002-08-14 EP disclosed
WO-2002049641-A2 ANTI-ENDOPARASITIC AMIDOACETONITRILS NOVARTIS AG (CH) 2002-06-27 WO disclosed
WO-2001040223-A2 AMINOHETEROCYCLYLAMIDES AS PESTICIDES AND ANTIPARASITIC AGENTS NOVARTIS AG (CH) 2001-06-07 WO disclosed
WO-2001036415-A1 PESTICIDAL AMINOHETEROCYCLAMIDE COMPOUNDS NOVARTIS AG (CH) 2001-05-25 WO disclosed
US-4970222-A INSECTICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-11-13 US disclosed
US-4879292-A Certain-phenoxy-phenoxy-alkylene-oxy-pyrimidines or symmetrical triazines, thio-analogues thereof, having insecticidal activity SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-07 US disclosed
EP-0128648-B1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-08-17 EP disclosed
US-4751225-A Certain 2-pyridyloxy-lower alkylene-oxy-phenoxy compounds, thio-and methylene analogues having insecticidal properties SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-14 US disclosed
EP-0128648-A1 Nitrogen-containing heterocyclic compounds, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-12-19 EP disclosed