Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2241803 | 1.00 | LMNA (0.46) | LMNASLC1A1TSHRMAPTGABRP | |
| SCHEMBL4537585 | 1.00 | LMNA (0.46) | LMNASLC1A1TSHRMAPTGABRP | |
| SCHEMBL22639581 | 0.89 | SLC1A1 (0.49) | LMNASLC1A1TSHRMAPTGABRP | |
| SCHEMBL16523558 | 0.89 | LMNA (0.43) | LMNASLC1A1TSHRMAPTGABRP | |
| SCHEMBL16523559 | 0.87 | LMNA (0.46) | LMNASLC1A1TSHRGABRPGABRD | |
| SCHEMBL31229067 | 0.87 | CYP1A2 (0.44) | LMNASLC1A1GABRPGABRDGABRA1 | |
| SCHEMBL14175423 | 0.87 | CYP1A2 (0.44) | LMNASLC1A1GABRPGABRDGABRA1 | |
| SCHEMBL2201201 | 0.84 | SLC1A1 (0.54) | LMNASLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL23515280 | 0.84 | SLC1A1 (0.36) | LMNASLC1A1GABRPGABRDGABRA1 | |
| SCHEMBL5885314 | 0.84 | SLC1A1 (0.36) | LMNASLC1A1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024224093-A1 | DESMURAMYLPEPTIDE DIEESTERS AS NOD2 AGONISTS AND USE THEREOF | Imhotex Limited (GB) | 2024-10-31 | — | — | WO | disclosed |
| CN-108794372-B | Novel compound and pharmaceutical composition for treating tuberculosis comprising same | 顺天乡大学校产学协力团 | 2021-09-14 | — | — | CN | disclosed |
| CN-105924380-B | Luxuriant and rich with fragrance class compound or derivatives thereof and treatment medicine for tuberculosis compositions containing the phenanthrene class compound or derivatives thereof | 顺天乡大学校产学协力团 | 2019-03-05 | — | — | CN | disclosed |
| CN-108794372-A | New compound and tuberculotherapy medical composition comprising it | 顺天乡大学校产学协力团 | 2018-11-13 | — | — | CN | disclosed |
| CN-105924380-A | Phenanthrene Compound, Ramification Thereof And Drug Composition Containing Phenanthrene Compound Or Ramification And Used For Treating Tuberculosis | 顺天乡大学校产学协力团 | 2016-09-07 | — | — | CN | disclosed |