Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 8/20 | 0.48 |
| ▸ | GAK | O14976 | 3/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28243561 | 0.86 | CDC7 (0.50) | NPC1MAPTPOLBMEN1KMT2A | |
| SCHEMBL1011248 | 0.80 | PABPC1 (0.59) | NPC1MAPTPOLBMEN1KMT2A | |
| SCHEMBL738379 | 0.80 | NPC1 (0.57) | NPC1MAPTPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL21436092 | 0.78 | NPC1 (0.55) | NPC1MAPTPOLBMEN1KMT2A | |
| SCHEMBL6313338 | 0.77 | EGFR (0.45) | NPC1MAPTPOLBMEN1KMT2A | |
| SCHEMBL6748149 | 0.77 | NPC1 (0.63) | NPC1MAPTPOLBMEN1KMT2A | |
| SCHEMBL1008997 | 0.77 | NPC1 (0.58) | NPC1MAPTPOLBMEN1KMT2A | |
| SCHEMBL31235641 | 0.77 | NPC1 (0.51) | NPC1MAPTPOLBMEN1KMT2A | |
| SCHEMBL15940145 | 0.77 | NPC1 (0.51) | NPC1MAPTPOLBMEN1KMT2A | |
| SCHEMBL5758552 | 0.75 | NPC1 (0.60) | NPC1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036006-A | The preparation and use of pyrimidone derivatives | 癌症研究科技有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-109689063-A | Nucleotide containing alkynes and nucleosides therapeutic combination and its associated uses | 埃默里大学 | 2019-04-26 | — | — | CN | disclosed |
| CN-109641056-A | Pharmaceutical composition | 协和发酵麒麟株式会社 | 2019-04-16 | — | — | CN | disclosed |
| CN-109134640-A | GM-CSF and IL-4 conjugates, composition and relative method | 爱默蕾大学 | 2019-01-04 | — | — | CN | disclosed |
| CN-104870477-B | GM-CSF and I L-4 conjugates, compositions, and methods related thereto | 爱默蕾大学 | 2018-10-09 | — | — | CN | disclosed |
| CN-106458821-A | BH4 antagonists and methods related thereto | 爱默蕾大学 | 2017-02-22 | — | — | CN | disclosed |
| CN-104470922-B | Pharmaceutical active compounds | 癌症研究科技有限公司 | 2016-08-24 | — | — | CN | disclosed |