SCHEMBL1011248

SCHEMBL1011248

c1ccc(Nc2ccc3ncccc3c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 1/20 0.59
NPC1 O15118 5/20 0.58
POLB P06746 2/20 0.58
MAPT P10636 2/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
ALDH1A1 P00352 7/20 0.58
HSD17B10 Q99714 2/20 0.58
HPGD P15428 2/20 0.58
ABCB1 P08183 1/20 0.58
ABCC1 P33527 1/20 0.58
ABCG2 Q9UNQ0 1/20 0.58
CYP3A4 P08684 1/20 0.58
KDM4E B2RXH2 2/20 0.55
GRM4 Q14833 1/20 0.55
EGFR P00533 1/20 0.54
RAB9A P51151 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.51
NAMPT P43490 1/20 0.51
TGFBR1 P36897 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2791886 0.92 ABCB1 (0.61) PABPC1NPC1POLBMAPTMEN1
SCHEMBL6748149 0.89 NPC1 (0.63) PABPC1NPC1POLBMAPTMEN1
SCHEMBL1008997 0.89 NPC1 (0.58) PABPC1NPC1POLBMAPTMEN1
SCHEMBL14582251 0.89 PABPC1 (0.52) PABPC1NPC1POLBMAPTMEN1
SCHEMBL25389520 0.86 ALDH1A1 (0.66) PABPC1NPC1POLBMAPTMEN1
SCHEMBL28242830 0.86 NPC1 (0.67) PABPC1NPC1POLBMAPTMEN1
SCHEMBL9702763 0.86 NPC1 (0.59) PABPC1NPC1POLBMAPTMEN1
SCHEMBL21101485 0.86 ALDH1A1 (0.58) PABPC1NPC1MAPTMEN1KMT2A
Diphenylamine SCHEMBL28251107 0.85 ALDH1A1 (0.71) PABPC1NPC1POLBMAPTMEN1
SCHEMBL16132944 0.85 ALDH1A1 (0.49) PABPC1NPC1POLBMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993011114-A1 AMINE ANTIDEGRADANTS FOR UNSATURATED POLYMERS UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-06-10 WO claimed
WO-2022181267-A1 TIRE 住友ゴム工業株式会社 2022-09-01 WO disclosed
WO-2022181269-A1 TIRE 住友ゴム工業株式会社 2022-09-01 WO disclosed
US-10573838-B2 Organic electric element comprising compound for organic electric element and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2020-02-25 US disclosed
US-10249825-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2019-04-02 US disclosed
US-10039759-B2 Quinolines as FGFR kinase modulators ASTEX THERAPEUTICS LTD (GB) 2018-08-07 US disclosed
US-20180205032-A1 ORGANIC ELECTRIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRIC ELEMENT AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-07-19 US disclosed
US-20180205032-A1 ORGANIC ELECTRIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRIC ELEMENT AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-07-19 US disclosed
EP-2009082-B1 Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine CHEVRON ORONITE CO (US) 2017-08-30 EP disclosed
WO-2017043835-A1 ORGANIC ELECTRONIC DIODE COMPOUND, ORGANIC ELECTRONIC DIODE USING SAME, AND DEVICE THEREFOR 덕산네오룩스 주식회사 2017-03-16 WO disclosed
US-20080318815-A1 SYNERGISTIC LUBRICATING OIL COMPOSITION CONTAINING A MIXTURE OF A NITRO-SUBSTITUTED DIARYLAMINE AND A DAIRYLAMINE CHEVRON ORONITE COMPANY LLC 2008-12-25 US disclosed
CN-101180273-A Methods of synthesizing 6-alkylaminoquinoline derivatives WYETH CORP (US) 2008-05-14 CN disclosed
EP-1883630-A2 METHODS OF SYNTHESIZING 6-ALKYLAMINOQUINOLINE DERIVATIVES Wyeth (US) 2008-02-06 EP disclosed
EP-1801104-A2 Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions Chevron Oronite Company LLC (US) 2007-06-27 EP disclosed
EP-1801189-A2 Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine Chevron Oronite Company LLC (US) 2007-06-27 EP disclosed
US-20070142243-A1 Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine CHEVRON ORONITE COMPANY LLC 2007-06-21 US disclosed
US-20070142246-A1 Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions CHEVRON ORONITE COMPANY LLC 2007-06-21 US disclosed
WO-2006127203-A2 METHODS OF SYNTHESIZING 6-ALKYLAMINOQUINOLINE DERIVATIVES WYETH (US) 2006-11-30 WO disclosed
US-20060270670-A1 Methods of synthesizing 6-alkylaminoquinoline derivatives WYETH 2006-11-30 US disclosed
WO-1993011114-A1 AMINE ANTIDEGRADANTS FOR UNSATURATED POLYMERS UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10039759-B2 Quinolines as FGFR kinase modulators FGFR1, FGFR3, FGFR2 PABPC1 4405/4885NPC1 2191/4885POLB 2415/4885
US-20060270670-A1 Methods of synthesizing 6-alkylaminoquinoline derivatives H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RECQL, NQO2 PABPC1 3923/4885NPC1 3471/4885POLB 1723/4885
US-20070142246-A1 Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions AHR, ARNT, HRH2 PABPC1 2603/4885NPC1 1276/4885POLB 129/4885
US-10249825-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof ORAI2, ESR1, OR51E2 PABPC1 3612/4885NPC1 4203/4885POLB 2028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.