Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28096522 | 0.98 | ALDH1A1 (0.54) | ALDH1A1POLBKMT2ATLR8SMN1; SMN2 | |
| SCHEMBL31346586 | 0.92 | ALDH1A1 (0.49) | ALDH1A1POLBKMT2ATLR8SMN1; SMN2 | |
| Bromide SCHEMBL28864315 | 0.90 | TLR8 (0.41) | ALDH1A1POLBKMT2ATLR8SMN1; SMN2 | |
| SCHEMBL28247432 | 0.90 | ALDH1A1 (0.46) | ALDH1A1POLBKMT2ATLR8SMN1; SMN2 | |
| SCHEMBL30833253 | 0.88 | TLR8 (0.42) | ALDH1A1POLBKMT2ATLR8SMN1; SMN2 | |
| Alanine SCHEMBL31346583 | 0.87 | SMN1; SMN2 (0.47) | ALDH1A1POLBKMT2ATLR8SMN1; SMN2 | |
| Cadaverine Tartrate SCHEMBL28180970 | 0.86 | ARG1 (0.44) | ALDH1A1POLBKMT2ATLR8SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL29275071 | 0.84 | TLR8 (0.49) | ALDH1A1POLBKMT2ATLR8SMN1; SMN2 | |
| Aspartic Acid SCHEMBL28246456 | 0.83 | ARG1 (0.47) | ALDH1A1POLBKMT2ATLR8SMN1; SMN2 | |
| SCHEMBL31415085 | 0.82 | ALDH1A1 (0.40) | ALDH1A1POLBKMT2ATLR8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119386635-A | Method and device for removing carbon dioxide in boron trifluoride-11 and adsorbent regeneration method | 昊华气体有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-116640048-B | Preparation method of 4,4' -biphenol | 江苏新瀚新材料股份有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116640048-A | Preparation method of 4,4' -biphenol | 江苏新瀚新材料股份有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-113880965-B | Ionic liquid modified chitosan derivative and preparation method and application thereof | 江苏西宏生物医药有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-113880965-A | Ionic liquid modified chitosan derivative and preparation method and application thereof | 江苏西宏生物医药有限公司 | 2022-01-04 | — | — | CN | claimed |
| CN-105949129-B | A kind of imidazoles bromide ionic liquid and its preparation method and application with amino | 辽宁大学 | 2019-02-19 | — | — | CN | claimed |
| CN-106478512-A | A kind of zinc-base glyoxaline ion liquid for fluid-tight and preparation method thereof | 林州市科能材料科技有限公司 | 2017-03-08 | — | — | CN | claimed |
| CN-119386635-A | Method and device for removing carbon dioxide in boron trifluoride-11 and adsorbent regeneration method | 昊华气体有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-116640048-B | Preparation method of 4,4' -biphenol | 江苏新瀚新材料股份有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116640048-A | Preparation method of 4,4' -biphenol | 江苏新瀚新材料股份有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-113880965-B | Ionic liquid modified chitosan derivative and preparation method and application thereof | 江苏西宏生物医药有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-113880965-A | Ionic liquid modified chitosan derivative and preparation method and application thereof | 江苏西宏生物医药有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-108794400-B | Amino acid-containing ionic liquid with amino group on cation, and preparation method and application thereof | 辽宁大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-105949129-B | A kind of imidazoles bromide ionic liquid and its preparation method and application with amino | 辽宁大学 | 2019-02-19 | — | — | CN | disclosed |
| CN-106045913-B | A kind of imidazoles perrhenate ions liquid and its preparation method and application with amino | 辽宁大学 | 2018-10-26 | — | — | CN | disclosed |
| CN-106478512-A | A kind of zinc-base glyoxaline ion liquid for fluid-tight and preparation method thereof | 林州市科能材料科技有限公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-106045913-A | Imidazolium perrhenate ionic liquid with amino groups as well as preparation method and application of imidazolium perrhenate ionic liquid | 辽宁大学 | 2016-10-26 | — | — | CN | disclosed |
| CN-105949129-A | Imidazolium bromide ionic liquid containing amine groups and preparation method and application of ionic liquid | 辽宁大学 | 2016-09-21 | — | — | CN | disclosed |