Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 7/20 | 0.42 |
| ▸ | CA12 | O43570 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 4/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CEL | P19835 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6789676 | 0.83 | NSD2 (0.45) | CA9CA12CA2GAALMNA | |
| SCHEMBL6788098 | 0.81 | LMNA (0.53) | HPGDGAALMNANPC1RAB9A | |
| SCHEMBL29019945 | 0.80 | CA9 (0.44) | HPGDCA9CA12CA2LMNA | |
| SCHEMBL6903338 | 0.79 | HPGD (0.58) | HPGDCA9CA12CA2LMNA | |
| SCHEMBL30367636 | 0.79 | HPGD (0.58) | HPGDCA9CA12CA2LMNA | |
| Hydrogen Sulfide SCHEMBL29165723 | 0.78 | HPGD (0.57) | HPGDCA9CA12CA2LMNA | |
| SCHEMBL23699758 | 0.72 | CYP2D6 (0.50) | CA9CA12CA2GAAELANE | |
| SCHEMBL21855131 | 0.71 | CYP2D6 (0.46) | CA9CA12CA2GAALMNA | |
| SCHEMBL27582170 | 0.68 | HPGD (0.44) | HPGDCA9CA12CA2ALDH1A1 | |
| SCHEMBL6789680 | 0.67 | CA12 (0.54) | HPGDCA9CA12CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008391-A | Preparation method of 2-phenyl-1,1-dioxo-1,2-benzisothiazole-3(2H)-one | 东华大学 | 2016-10-12 | — | — | CN | disclosed |