Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 11/20 | 0.64 |
| ▸ | CA1 | P00915 | 10/20 | 0.64 |
| ▸ | CA2 | P00918 | 10/20 | 0.64 |
| ▸ | CA12 | O43570 | 9/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.64 |
| ▸ | CA7 | P43166 | 3/20 | 0.64 |
| ▸ | CA4 | P22748 | 2/20 | 0.64 |
| ▸ | CA3 | P07451 | 2/20 | 0.64 |
| ▸ | CA6 | P23280 | 2/20 | 0.64 |
| ▸ | CA5A | P35218 | 2/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.64 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.64 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzenesulfonamide SCHEMBL28157768 | 0.90 | CA9 (0.52) | CA9CA1CA2CA12CA14 | |
| Benzenesulfonamide SCHEMBL4893393 | 0.87 | CA1 (0.76) | CA9CA1CA2CA12CA14 | |
| Benzenesulfonamide SCHEMBL28658299 | 0.85 | CA2 (0.73) | CA9CA1CA2CA12CA14 | |
| SCHEMBL284012 | 0.85 | CA2 (0.73) | CA9CA1CA2CA12CA14 | |
| Benzenesulfonamide SCHEMBL9491339 | 0.83 | CA2 (0.84) | CA9CA1CA2CA12CA14 | |
| Acetophenone SCHEMBL30518145 | 0.82 | MAPT (0.68) | CA9CA1CA2CA12CA14 | |
| SCHEMBL3347957 | 0.82 | CA2 (0.63) | CA9CA1CA2CA12CA14 | |
| Benzenesulfonamide SCHEMBL28378396 | 0.82 | CA2 (0.73) | CA9CA1CA2CA12CA14 | |
| Acetophenone SCHEMBL28282887 | 0.82 | SMN1; SMN2 (0.67) | CA9CA12SMN1; SMN2KDM4EMAPT | |
| Benzenesulfonamide SCHEMBL19348104 | 0.81 | CA2 (0.80) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008305-A | Synthetic method of penta-substituted 2-amino pyrrole derivatives | 陕西师范大学 | 2016-10-12 | — | — | CN | disclosed |