Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12502138 | 0.87 | CYP19A1 (0.45) | CYP19A1TSHRALDH1A1ACHECHRNB2 | |
| SCHEMBL2809637 | 0.86 | ALOX15 (0.33) | CYP19A1TSHRALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL27516786 | 0.86 | TET2 (0.34) | CYP19A1ALDH1A1CHRNB2CHRNA4ALOX15 | |
| SCHEMBL9064550 | 0.85 | — | — | |
| SCHEMBL23926234 | 0.82 | MGAM (0.44) | CYP19A1MAPTBLMALDH1A1ACHE | |
| SCHEMBL27756760 | 0.81 | THRB (0.36) | CYP19A1MAPTTSHRALDH1A1ACHE | |
| SCHEMBL12502152 | 0.81 | CYP19A1 (0.36) | CYP19A1BLMTSHRACHEAPEX1 | |
| SCHEMBL11646251 | 0.80 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL2019215 | 0.80 | TSHR (0.33) | CYP19A1TSHRCHRNB2CHRNA4ALOX15 | |
| SCHEMBL2025630 | 0.80 | TSHR (0.33) | CYP19A1TSHRALDH1A1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240824-A1 | POWDER COATING SUSPENSIONS (POWDER SLURRIES) AND POWDER COATING MATERIALS, THEIR PREPARATION AND USE | BASF COATINGS AG (DE) | 2010-09-23 | — | — | US | claimed |