SCHEMBL2809651

SCHEMBL2809651

C=C(C)C(=O)OC(C)OP(=O)([O-])OC[N+](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ADRA1D P25100 1/20 0.32
PTAFR P25105 1/20 0.32
HTR1D P28221 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1B P35368 1/20 0.32
DRD3 P35462 1/20 0.32
TMEM97 Q5BJF2 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30
PLA2G10 O15496 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL529986 0.87 SMN1; SMN2 (0.46) ADRA1DPTAFRHTR1DHTR2CADRA1B
SCHEMBL17595251 0.76 FABP3 (0.38) TSHRADRA1DPTAFRHTR1DHTR2C
SCHEMBL14740535 0.76 ALDH1A1 (0.31) TSHR
Potassium Ion SCHEMBL11653244 0.75 TSHR (0.37) TSHR
SCHEMBL985644 0.72 TSHR (0.41) TSHR
SCHEMBL3516495 0.72 ADRA1D (0.33) TSHRADRA1DPTAFRHTR1DHTR2C
Choline SCHEMBL29084705 0.71 TSHR (0.33) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL1225864 0.71 SMN1; SMN2 (0.53) TSHRADRA1DPTAFRHTR1DHTR2C
SCHEMBL170329 0.71 TSHR (0.39) TSHR
SCHEMBL137325 0.71 TSHR (0.39) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE40816-E1 Biocompatible crosslinked coating and crosslinkable coating polymer composition for forming such a coating BIOCOMPATIBLES UK LIMITED (GB) 2009-06-30 US claimed
US-8075609-B2 Expandable stent EVYSIO MEDICAL DEVICES ULC (CA) 2011-12-13 US disclosed
EP-1790314-B1 Expandable stent EVYSIO MEDICAL DEVICES ULC (CA) 2010-06-16 EP disclosed
US-20090192590-A1 EXPANDABLE STENT AND METHOD FOR DELIVERY OF SAME EVYSIO MEDICAL DEVICES ULC (CA) 2009-07-30 US disclosed
US-RE40816-E1 Biocompatible crosslinked coating and crosslinkable coating polymer composition for forming such a coating BIOCOMPATIBLES UK LIMITED (GB) 2009-06-30 US disclosed
US-RE40816-E1 Biocompatible crosslinked coating and crosslinkable coating polymer composition for forming such a coating BIOCOMPATIBLES UK LIMITED (GB) 2009-06-30 US disclosed
US-20090036974-A1 EXPANDABLE STENT AND METHOD FOR DELIVERY OF SAME EVYSIO MEDICAL DEVICES ULC (CA) 2009-02-05 US disclosed
US-20080021542-A1 Expandable Stent And Method For Delivery Of Same EVYSIO MEDICAL DEVICES ULC (CA) 2008-01-24 US disclosed
US-20080021536-A1 EXPANDABLE STENT AND METHOD FOR DELIVERY OF SAME EVYSIO MEDICAL DEVICES ULC (CA) 2008-01-24 US disclosed
EP-1477133-B9 Expandable stent EVYSIO MEDICAL DEVICES ULC (CA) 2007-11-21 EP disclosed
EP-1066804-A2 Expandable stent DIVYSIO SOLUTIONS ULC. (CA) 2001-01-10 EP disclosed
US-6083257-A Braided stent BIOCOMPATIBLES LIMITED (GB) 2000-07-04 US disclosed
EP-0994682-A1 EXPANDABLE STENT Novo RPS ULC (CA) 2000-04-26 EP disclosed
WO-1999002105-A1 EXPANDABLE STENT NOVO RPS ULC (CA) 1999-01-21 WO disclosed
EP-0888094-A1 EXPANDABLE STENT AND METHOD FOR DELIVERY OF SAME Divysio Solutions ULC (CA) 1999-01-07 EP disclosed
EP-0888093-A1 EXPANDABLE STENT AND METHOD FOR DELIVERY OF SAME Divysio Solutions ULC (CA) 1999-01-07 EP disclosed
EP-0858299-A1 BRAIDED STENT BIOCOMPATIBLES LIMITED (GB) 1998-08-19 EP disclosed
WO-1997032544-A1 EXPANDABLE STENT AND METHOD FOR DELIVERY OF SAME DIVYSIO SOLUTIONS ULC. (CA) 1997-09-12 WO disclosed
WO-1997032543-A1 EXPANDABLE STENT AND METHOD FOR DELIVERY OF SAME DIVYSIO SOLUTIONS ULC. (CA) 1997-09-12 WO disclosed
WO-1997016133-A1 BRAIDED STENT BIOCOMPATIBLES LIMITED (GB) 1997-05-09 WO disclosed